lentigo maligna


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lentigo

 [len-ti´go] (L.)
a flat, brownish pigmented spot on the skin due to increased deposition of melanin and an increased number of melanocytes; a freckle. (See Atlas 2, Part O.)
lentigo malig´na (malignant lentigo) see lentigo maligna melanoma.
senile lentigo (lentigo seni´lis,) (solar lentigo) a small smooth round brownish patch appearing on the face, neck, or back of the hands of many older people, caused by an increase in pigment; these are entirely harmless. Although these spots are associated with aging, it is not age that is the principal cause but many years of exposure to sun and wind. Called also liver spot.

len·ti·go ma·lig·na

a brown or black mottled, irregularly outlined, slowly enlarging lesion resembling a lentigo in which there are increased numbers of scattered atypical melanocytes in the epidermis, usually occurring on the face of older persons; after many years the dermis may be invaded and the lesion is then termed lentigo maligna melanoma.

lentigo maligna

lentigo maligna

Hutchinson's melanotic freckle, lentigo maligna melanoma
A lesion comprising 10% of melanomas, affects those > age 60; flat, indolent, arises in premalignant freckle, located on sun-exposed aging skin; begins as an unevenly pigmented macule with an irregular border, slowly extends peripherally Etiology Solar overexposure,13 progress to melanoma in 10-15 yrs Prognosis > 95% 5-yr survival. See Lentigo, Melanoma.

len·ti·go ma·lig·na

(len-tī'gō mă-lig'nă)
A brown or black mottled, irregularly outlined, slowly enlarging lesion resembling a lentigo in which there are increased numbers of scattered atypical melanocytes in the epidermis, usually occurring on the face of older persons; after many years the dermis may be invaded and the lesion is then termed lentigo maligna melanoma.
Synonym(s): Hutchinson freckle.
Enlarge picture
LENTIGO MALIGNA: SOURCE: Centers for Disease Control and Prevention; Carl Washington, MD

lentigo maligna

A pigmented lesion of the skin in which a large number of superficial, atypical melanocytes are found. Synonym: Hutchinson's freckle
See: illustration
See also: lentigo

Hutchinson,

Sir Jonathan, English surgeon and pathologist, 1828-1913.
Hutchinson crescentic notch - the semilunar notch on the incisal edge of Hutchinson teeth, encountered in congenital syphilis.
Hutchinson disease - age-related guttate choroiditis.
Hutchinson facies - the peculiar facial expression produced by drooping eyelids and motionless eyes in external ophthalmoplegia.
Hutchinson freckle - a brown or black mottled, irregularly outlined, slowly enlarging lesion. Synonym(s): lentigo maligna
Hutchinson mask - the sensation experienced in tabetic neurosyphilis as if the face were covered with a mask or with cobwebs.
Hutchinson patch - interstitial or parenchymatous keratitis giving rise to neovascularization of the cornea. Synonym(s): salmon patch
Hutchinson pupil - dilation of the pupil on the side of the lesion as part of a third nerve palsy.
Hutchinson teeth - the teeth of congenital syphilis in which the incisal edge is notched and narrower than the cervical area. Synonym(s): notched teeth; screwdriver teeth; syphilitic teeth
Hutchinson triad - parenchymatous keratitis, labyrinthine disease, and Hutchinson teeth, significant of congenital syphilis.
Hutchinson-Gilford disease - a condition in which normal development in the first year is followed by gross retardation of growth, with dry wrinkled skin, total alopecia, and birdlike facies. Synonym(s): Hutchinson-Gilford syndrome; progeria
Hutchinson-Gilford syndrome - Synonym(s): Hutchinson-Gilford disease
References in periodicals archive ?
dagger]) RGP indicates radial growth phase; VGP, vertical growth phase; SSM, superficial spreading melanoma; LMM, lentigo maligna melanoma; ALM, acral lentiginous melanoma; NM, nodular melanoma; and DM, desmoplastic melanoma.
Increasing incidence of lentigo maligna melanoma subtypes: northern California and national trends 1990-2000.
McKenna JK, Florell SR, Goldman GD, Bowen GM: Lentigo maligna/ lentigo maligna melanoma: current state of diagnosis and treatment.
Comparison between lentigo maligna melanoma and other hystogenetic types of malignant melanoma of the head and neck.
Lentigo maligna melanoma represents approximately 10% of melanomas and typically presents as a slowly enlarging, asymmetric, brown to black macule with irregular pigmentation on sun-exposed skin.
For "banal"-appearing firm lesions on chronically sun-damaged skin, suspicion should be raised if the lesions are symptomatic, growing, are associated with a lentigo maligna, or reveal irregular vessels with dermoscopy, said Dr.
Hastalarimizin klinik ve dermatoskopik tanilari Tani Lezyon sayisi (%) Junctional nevus 183 (%20) Compound nevus 179 (%19,8) Dermal nevus 176 (%19,5) Konjenital 138 (%15,2) melanositik nevus Lentigo 39 (%4,3) Seboreik keratoz 39 (%4,3) Kafeola 39 (%4,3) Displastik nevus 32 (%3,5) Akrokordon 19 (%2,1) Hemanjiyom 13 (%1,4) Akral 11 (%1,2) melanositik nevus Nevus spilus 9 (%1) Blue nevus 8 (%0,8) Dermatofibrom 8 (%0,8) Aktinik keratoz 5 (%0,5) Bazal hucreli 1 (%0,1) karsinom Yuzeyel yayilan 1 (%0,1) melanom Digerleri: Efelid, 4 (%0,4) Lentigo maligna, Bowen hastaligi, Aksesuar meme
The other subtypes are superficial spreading malignant melanoma, nodular melanoma, and lentigo maligna melanoma.
Amelanotic lentigo maligna melanoma: a unique case presentation.
Lentigo maligna are also precursors and 5% of all melanomas arise from these types of lesions.
The evidence linking sun exposure to melanoma is the strongest for the least common type of lentigo maligna melanoma.
Bowen has been working to improve the surgical treatment of lentigo maligna ever since he joined the Huntsman Cancer Institute at the University of Utah, Salt Lake City, 16 years ago.