leiomyoma

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Related to leiomyomata: Uterine fibroids, Uterine leiomyomata

leiomyoma

 [li″o-mi-o´mah]
a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri).
bizarre leiomyoma epithelioid leiomyoma.
leiomyoma cu´tis one arising from cutaneous or subcutaneous smooth muscle fibers, found singly or multiply, usually as lesions arising from arrectores pilorum muscles; it may also occur as a solitary genital lesion or a solitary angioleiomyoma arising from the muscle of veins.
epithelioid leiomyoma one in which the cells are polygonal rather than spindle shaped, usually found in the stomach. Called also bizarre leiomyoma and leiomyofibroma.
leiomyoma u´teri (uterine leiomyoma) leiomyoma of the uterus; called also uterine myoma and, colloquially, fibroids. It is the most common of all tumors found in women. It may occur in any part of the uterus, although it is most frequently in the body of the organ.

Leiomyomas usually occur during the third and fourth decades, and are often multiple, although a single tumor may occur. They are usually small but may grow quite large and occupy most of the uterine wall; after menopause, growth usually ceases. Symptoms vary according to the location and size of the tumors. As they grow they may cause pressure on neighboring organs, painful menstruation, profuse and irregular menstrual bleeding, vaginal discharge, or frequent urination, as well as enlargement of the uterus.

In pregnancy, the tumors may interfere with natural enlargement of the uterus with the growing fetus. They may also cause spontaneous abortion and death of the fetus.

Small leiomyomas are usually left undisturbed and are checked at frequent intervals. Larger tumors may be removed surgically, sometimes accompanied by a hysterectomy, or medication may be prescribed to induce a temporary menopause.
Leiomyoma of the uterus. The tumors may be subserosal, intramural, or submucosal. Subserosal and submucosal tumors may be pedunculated and may protrude from the uterine surface or into the uterine cavity, respectively. The stalk of pedunculated tumors may also become twisted. From Damjanov, 2000.

lei·o·my·o·ma

(lī'ō-mī-ō'mă),
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma

/leio·myo·ma/ (-mi-o´mah) a benign tumor derived from smooth muscle, most often of the uterus.
leiomyoma cu´tis  one or more smooth, firm, painful, often waxy nodules arising from cutaneous or subcutaneous smooth muscle fibers.
epithelioid leiomyoma  leiomyoma, usually of the stomach, in which the cells are polygonal rather than spindle shaped.

leiomyoma

(lī′ō-mī-ō′mə)
n. pl. leiomyo·mas or leiomyo·mata (-mə-tə)
A benign tumor derived from smooth muscle, occurring most often in the uterus.

lei′o·my·o′ma·tous (-ō′mə-təs, -ŏm′ə-) adj.

leiomyoma

[lī′ōmī·ō′mə] pl. leiomyomas, leiomyomata
a benign smooth-muscle tumor occurring most commonly in the uterus, stomach, esophagus, or small intestine. Surgical resection is usually indicated.
enlarge picture
Leiomyomas

leiomyoma

Fibroma, plural, leiomyomata or, incorrect, but increasingly popular, leiomyomas A benign, well-circumscribed smooth muscle tumor most common in the uterus and stomach. See Fibroid, Fibroma, Intestinal leiomyoma.

lei·o·my·o·ma

(lī'ō-mī-ō'mă)
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma

A benign tumour of smooth muscle found most commonly in the womb (uterus). Leiomyomas often contain much fibrous tissue. Also known as FIBROID, fibromyoma or leiomyofibroma.

Leiomyoma

A benign tumor composed of muscle tissue. Leiomyomas in the uterus are sometimes called fibroids.
Mentioned in: Hysterosonography

leiomyoma

vascular smooth-muscle-derived benign neoplasm; firm, smooth subcutaneous nodule with associated local stabbing pain; treated by local excision

lei·o·my·o·ma

(lī'ō-mī-ō'mă)
A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]

leiomyoma (lī´ōmīō´mə),

n a benign tumor derived from smooth muscle.

leiomyoma

a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri) but can occur in urinary bladder, upper intestinal tract and esophagus.

leiomyoma uteri
leiomyoma of the uterus; called also colloquially, fibroids.

Patient discussion about leiomyoma

Q. uterine fibroids. Whats the best way to deal with them? My doctor says hysterectomy? What about my hormones?

A. Yes, drugs that suppress the levels of the female sex hormones (estrogen) are successful for treating uterine fibroids. However, the relief is only temporary and the fibroids recur once the treatment is stopped. In addition, these treatments cause side effects similar to menopause.

Surgery is the definitive treatment, especially for complications such as bleeding or pain, and when there's a suspicion for malignancy.

You may read more here: http://www.nlm.nih.gov/medlineplus/ency/article/000914.htm

More discussions about leiomyoma
References in periodicals archive ?
Although VEGF seems to be a highly specific mitogen for vascular endothelial cells, VEGF mRNA and VEGF protein expression have now been identified in the smooth muscle cells of both myometrium and leiomyomata (Dixon et al.
This may include hys-teroscopic myomectomy on a leiomyomata previously believed to be located away from the endometrial cavity.
Epidemiologic contributions to understanding the etiology of uterine leiomyomata.
We then place an 8-mm port in the left and right lower quadrants, placing them more cephalad and lateral in the case of larger uteri or leiomyomata.
Tumor size--determined by pathology report--was also significant in an inverse direction, with the largest tumors (greater than 6 cm) predicting the lowest recurrence rate (17% of 23 women), the smallest ones (2-4 cm) having the highest recurrence (41% of 59), with the medium-sized leiomyomata (4-6 cm) in between (30% of 27).
Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15.
Identified risk factors for PPH after an elective operation included leiomyomata, placenta previa, antepartum bleeding, preterm birth, and general anesthesia.
Uterine leiomyomata and decreased height: a common HMGA2 predisposition allele.
Although uterine leiomyomata are asymptomatic in 50% of cases, they may cause menorrhagia, dysmenorrhoea, abdominal swelling and pressure symptoms (3).
Surgeons should also familiarise themselves with other techniques of tissue extraction, especially in cases where the diagnosis of benign leiomyomata is less certain.
BACKGROUND: Uterine leiomyomata (fibroids) are hormonally responsive tumors, but little is known about risk factors.
Fibroids, also known as uterine leiomyomata, are noncancerous tumors of the uterus.