lead compound


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lead compound

A peptide, small molecule, or other agent with pharmacological or biochemical properties which suggest that it may have therapeutic potential and value as a starting point for drug development.
References in periodicals archive ?
motivation to modify the lead compound, there must be some likelihood of
Financing will be used to advance Avexxin's lead compound against psoriasis.
The company's lead compound, ThGRF, is an analogue of a natural hormone known as growth hormone releasing factor.
The old reporting threshold required facilities to report lead and lead compound emissions to air, water and land if they annually manufactured or processed more than 25,000 pounds (55,000 kilograms).
To gain marketing approval for our lead compound DAVANAT([R]) would be a major milestone in the development of our technology.
Carna Biosciences will handle compound screening and construct a protein expression system and CrystalGenomics will analyze the structure of Cdc7-ASK and optimize a lead compound.
It will allow us to focus on continuing clinical trials of our lead compound, ACPC, for neuroprotection, moving new compounds into preclinical trials and on increasing our scientific capabilities.
NOV-002, the lead compound currently in Phase 3 development for lung cancer under a SPA and Fast Track, acts together with chemotherapy as a chemoprotectant and an immunomodulator.
HPI's lead compound, HP 228, recently began human clinical trials and will be investigated in several important inflammatory diseases.
To gain FDA marketing approval for our lead compound DAVANAT([R]) would be a major milestone in the development of our technology.
Othera's lead compound, OT-551, an eye drop, is being developed to treat several major eye diseases and conditions, including the dry and wet forms of age-related macular degeneration (AMD), cataracts, ocular allergy and dry eye syndrome.