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latanoprost |
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latanoprost /la·tan·o·prost/ (lah-tan´o-prost″) an antiglaucoma agent applied topically to the conjunctiva in the treatment of open-angle glaucoma and ocular hypertension.
latanoprost [lah-tan′o-prost′] an agent applied topically to the conjunctiva for treatment of open-angle glaucoma and ocular hypertension. latanoprost a prostaglandin F2alpha analog used topically to reduce intraocular pressure in the treatment of glaucoma in dogs.
prostaglandin analogues Drugs used in the treatment of open-angle glaucoma or ocular hypertension. At specific dosages they lower the intraocular pressure (IOP), supposedly by increasing the outflow of aqueous humour via the uveoscleral pathway. Common agents include latanoprost, travoprost, bimatoprost (a synthetic prostamide structurally related to prostaglandin) and unoprostone isopropyl. Bimatoprost reduces IOP by increasing the uveoscleral outflow as well as the trabecular outflow.
latanoprost Xalatan™ Ophthalmology An agent used to ↓ intraocular pressure in Pts with 1º and 2º glaucoma. See Glaucoma. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Again, the agent demonstrated an eye pressure-lowering effect, but any favorable result was obtained from a non-inferiority study in which DE-085 was compared with latanoprost. In a comment for clients, Robert Uhl, an analyst at Salomon Brothers, said, ``In our view, Allergan's existing businesses in ophthalmic products would provide a strong vehicle for Pharmacia & Upjohn to launch its soon-to-be-introduced therapy for glaucoma, Latanoprost. Johan Stjernschantz, Professor of Pharmacology and Drug Development, and Bahram Resul, Associate Professor of Medicinal Chemistry, are the inventors of latanoprost, the active principle of Xalatan[R]. |
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