laminin


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lam·i·nin

(lam'i-nin),
A large, multimeric glycoprotein component of the basement membrane, particularly the lamina lucida; it has binding sites for integrins, type IV collagen, and heparan sulfate. It is a major protein component of the lamina lucida of the renal glomerulus.

laminin

(lăm′ə-nĭn)
n.
Any of a family of glycoproteins that are components of the basement membrane and mediate cell proliferation, migration, differentiation, and adhesion.

laminin

[lam′inin]
any of several large glycoproteins consisting of three polypeptide subunits and found in basement membranes. It facilitates linkage with collagen and other basement membrane components and is involved in neurite regeneration.
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Laminin

laminin

a hetero-trimeric linking protein of the BASAL LAMINA. Laminin induces ADHESION and the spreading of many cell types, promotes CHEMOTAXIS and CELL DIFFERENTIATION and the outgrowth of NEURITES in culture.

lam·i·nin

(LN) (lam'i-nin)
A large, multimeric glycoprotein component of the basement membrane, particularly the lamina lucida; it has binding sites for integrins, type IV collagen, and heparan sulfate. It is a major protein component of the lamina lucida of the renal glomerulus.

laminin

(lam´ənən),
n a large polypeptide glycoprotein component of the basement membrane.

laminin

a glycoprotein found in basement membrane.
References in periodicals archive ?
LAMA2-congenital muscular dystrophy-related dystrophy (also known as congenital muscular dystrophy with laminin a2 deficiency, merosin-deficient congenital muscular dystrophy, MDC1A)
In recent years, some studies have proposed non-invasive, serum-based biomarkers: HA, laminin (LN), collagen IV (C-IV) and amino-terminal pro-peptide of Type-III pro-collagen (PIIINP) as indices of the extent of liver fibrosis in chronic liver diseases.
To obtain laminin (Sigma-Aldrich, USA)-coated culture dishes, 2 mL of 40 [micro]g/mL laminin solution were spread onto 35-mm Petri dishes and incubated for 2 h at 37[degrees]C.
It contains a variety of specialized proteins such as fibronectin, laminin, proteoglycans, glycosaminoglycan's and collagen type IV, V and VII.
Type IV collagen, a network-forming n type,14 and laminins are the most abundant building blocks of the basement membrane.
Thus, conventional methods of decellularization have many drawbacks like lower quantity and quality of glycosaminoglycans (GAGs) / fibronectin / heparin sulfate/ laminin /collagen IV / bFGF etc.
a) Triple-immunofluorescent stained for laminin (green), Pax7 (red), and nuclei (blue).
E-cadherin, laminin and collagen IV antibodies were obtained from Abeam (Cambridge, UK), [alpha]-SMA antibody was purchased from DAKO (Produktionsvej 42, DK2600 Glostrup, Denmark).
Naturally derived biopolymers such as derivatives of carbohydrates and collagen, elastin, laminin, and fibronectin are used for drug delivery and skin soft tissue utilization.
Carcinoma cells have the ability to transform fibroblasts into reactive myofibroblasts, which synthesize different ECM components: collagen, fibronectin, tenascin, versican, galectin, laminin and others.
Within the central nervous system, extracellular matrix substances such as collagen and laminin promote the regeneration, differentiation, adhesion and migration of nerve fibers.
ECM consists of several distinct components (Figure 1) which can be divided into three groups: i) structural proteins, such as collagen and elastin, ii) specialized adhesion proteins, such as fibronectin, fibrilin, and laminin, iii) glycosaminoglycans (GAG) and proteoglycans (PG).