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lamellipodium |
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lamellipodium pl. lamellipodia [L., Gr.] delicate sheetlike extension of cytoplasm that forms transient adhesions with the cell substrate and waves gently, enabling the cell to move along the substrate. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Interestingly, fluorescence speckle microscopy analysis of the dynamics of actin and Arp2/3 complex in the lamellipodial branched filament array of migrating Drosophila S2 ceils also show that like in the biomimetic system, Arp2/3 is incorporated into the network at the cell edge and undergoes treadmilling-driven retrograde flow at the same rate of 2. As seen in Figure 6C, LPS- (c) and TNF-a- (e) induced actin localization to lamellipodial extensions. The kymograph analysis showed that this is not due to reduced lamellipodial protrusion but rather to excessive retractions due to an apparent instability of cell contacts formed on the 108-nm-spaced pattern. |
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