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lactam |
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lactam /lac·tam/ (lak´tam) a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams. ) ß-lactam see under antibiotic.
lactam a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams. ß-lactam antibiotics includes the penicillins, cephalosporins, carbapenems and penems. See also ß-lactam ring (below). ß-lactam ring an integral part of the formula of ß-lactam antibiotics. Disruption of the ring by ß-lactamase produced by some bacteria, e.g. Escherichia coli, Bacillus anthracis, destroys the antimicrobial activity of the compound. |
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Because the mycoplasma organism produces no cell wall, beta lactam drugs (penicillin) have no affect on the organism. Abstract: Methylene acceptors are prepared by reacting a polyhydric phenol with an aromatic olefinic compound in the presence of an acid catalyst, and then further reacting with an N-methylol lactam derivative. Named Hanhwa Lactam, the joint venture will have a total production capacity of 140,000 metric tons that will be executed in stages beginning with an initial annual output of 70,000 metric tons. |
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