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cloverleaf skull; a congenital anomaly in which there is intrauterine synostosis of multiple or all cranial sutures.
clo·ver·leaf skull syn·drome[MIM*148800]
intrauterine bone dysplasia and synostosis of the coronal and lambdoid sutures of the cranium producing a trilobar head shape, sometimes associated with exophthalmos, and various craniofacial and long-bone anomalies; the condition is sporadic.
kleeblattschädel/klee·blatt·schä·del/ (kla´blaht-sha´d'l) [Ger.] cloverleaf skull; a congenital anomaly in which there is intrauterine synostosis of multiple or all cranial sutures.
Aetiology Thanatophoric dwarfism [MIM 148800], accompanied by a prominent forehead, depressed nasal bridge, shortened limbs, bowing of femora, epiphyseal cupping, flattened vertebral bodies, achondroplasia-like pelvis, often, but not invariably, associated with mental retardation