kininogen /ki·nin·o·gen/ (ki-nin´o-jen) either of two plasma α2-globulins that are kinin precursors, HMW (high-molecular-weight) k., precursor to bradykinin, and LMW (low-molecular-weight) k., precursor to kallidin.
kininogen [ki-nin´o-jen″]
ki·nin·o·gen (k -n n  -jn, -j n )n. The inactive globulin precursor of a plasma kinin. |
kininogen [ki-nin´o-jen″]
either of two plasma α2-globulins that are kinin precursors. High-molecular-weight (HMW) kininogen (also called Fitzgerald factor) is split by plasma kallikrein to produce bradykinin; low-molecular-weight (LMW) kininogen is split by tissue kallikrein to produce kallidin. Deficiency of HMW kallikrein is a rare condition but may be considered when prolonged activated partial thromboplastin time cannot be explained by deficiencies of other more common factors.
kininogen
an α2-globulin of plasma that is a precursor of the kinins.
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