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kininogen

   Also found in: Wikipedia 0.03 sec.
kininogen /ki·nin·o·gen/ (ki-nin´o-jen) either of two plasma α2-globulins that are kinin precursors, HMW (high-molecular-weight) k., precursor to bradykinin, and LMW (low-molecular-weight) k., precursor to kallidin.
ki·nin·o·gen (k-nn-jn, -jn)
n.
The inactive globulin precursor of a plasma kinin.
kininogen
an α2-globulin of plasma that is a precursor of the kinins.


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Kallikrein is a serine protease that cleaves kininogen to produce kinin, a vasoactive and natriuretic peptide (Clemems 1989; Schmaier 2003).
Identification of putative gene-based markers of renal toxicity by Afshari, Cynthia A. / Environmental Health Perspectives
When a detailed analysis of coagulation values was indicated, it included repeated measurements of the CBC, PT, aPTT, bleeding time, von Willebrand's antigen and activity, collagen-binding activity, high-molecular-weight kininogen, and the activity and concentration of factors I, II, V, VII, VIII, IX, X, XI, XII, and XIII.
Unidentified coagulation disorders in post-tonsillectomy hemorrhage by Remmert, Stephan / Ear, Nose and Throat Journal
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