kininase II


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kininase II

/ki·nin·ase II/ (-ās) see peptidyl-dipeptidase A.
References in periodicals archive ?
ACE inhibitors block kininase II, an enzyme necessary for bradykinin catabolism, which leads to an accumulation of bradykinin in the patient's bloodstream.
1-3) Angioedema due to ACE inhibitors appears to be linked to the decreased degradation of bradykinin because ACE, also known as kininase II, not only activates angiotensin I but also inactivates bradykinin.
ACE, also known as kininase II, is a bivalent dipeptidyl carboxyl zinc metalloproteinase that catalyzes the conversion of angiotensin I to the potent vasoconstrictor, angiotensin II.