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kininase |
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kininase an enzyme that rapidly inactivates kinin found in tissues and plasma. There are two types: kininase I, which is a carboxypeptidase; and kininase II, which is an angiotensin-converting enzyme. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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1-3) Angioedema due to ACE inhibitors appears to be linked to the decreased degradation of bradykinin because ACE, also known as kininase II, not only activates angiotensin I but also inactivates bradykinin. Angiotensin II (formed from angiotensin I in a reaction catalyzed by angiotensin converting enzyme (ACE, kininase II)), is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension. ACE, also known as kininase II, is a bivalent dipeptidyl carboxyl zinc metalloproteinase that catalyzes the conversion of angiotensin I to the potent vasoconstrictor, angiotensin II. |
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