keratomalacia


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Related to keratomalacia: xerophthalmia, Bitot's spots, follicular hyperkeratosis

keratomalacia

 [ker″ah-to-mah-la´she-ah]
softening and necrosis of the cornea associated with vitamin A deficiency.

ker·a·to·ma·la·ci·a

(ker'ă-tō-mă-lā'shē-ă),
Dryness with ulceration and perforation of the cornea, with absence of inflammatory reactions, occurring in cachectic children; results from severe vitamin A deficiency.
Synonym(s): xerotic keratitis
[kerato- + G. malakia, softness]

keratomalacia

/ker·a·to·ma·la·cia/ (ker″ah-to-mah-la´shah) softening and necrosis of the cornea associated with vitamin A deficiency.

keratomalacia

[-məlā′shə]
Etymology: Gk, keras + malakia, softness
a condition characterized by xerosis and ulceration of the cornea, resulting from severe vitamin A deficiency. It commonly occurs as a secondary result of diseases that affect vitamin A absorption or storage, such as ulcerative colitis, celiac syndrome, cystic fibrosis, and sprue. Also at risk are infants and children who are given dilute formula, who are malnourished, or who are allergic to whole milk and fed skimmed milk, which is a poor source of vitamin A. Early symptoms include night blindness; photophobia; swelling and redness of the eyelids; and drying, roughness, pain, and wrinkling of the conjunctiva. In advanced deficiency, Bitot's spots appear; the cornea becomes dull, lusterless, and hazy, and without adequate therapy it eventually softens and perforates, resulting in blindness. See also vitamin A.
interventions Treatment consists of vitamin A supplements. The dosage is determined by the severity of the condition, although prolonged daily administration of large doses, especially to infants, may result in hypervitaminosis. An adequate diet containing whole milk and foods high in vitamin A or carotenes prevents the condition.

ker·a·to·ma·la·ci·a

(ker'ă-tō-mă-lā'shē-ă)
Dryness with ulceration and perforation of the cornea occurring in cachectic children; results from severe vitamin A deficiency.
[kerato- + G. malakia, softness]

keratomalacia

Softening or ‘melting’ of the cornea usually in severely malnourished children whose body stocks of vitamin A have become exhausted. Corneal melt leads to internal infection and irremediable blindness and this is the fate of millions of children every year in economically depressed parts of the world. A small regular dose of vitamin A, as from a few fleshy green leaves, will prevent this.

Keratomalacia

Keratomalacia is ulceration of the cornea.
Mentioned in: Vitamin A Deficiency

keratomalacia

Vitamin A deficiency in which the cornea becomes desiccated at first and then softens, at which stage it is associated with infiltration, pannus, necrosis, opacification and the eye becomes blind. There is also a lack of reaction to inflammation leading to a destruction of the eye if infection occurs. It is part of a general systemic condition due to malnutrition. Associated with this condition are night blindness, faulty growth of bone, xerophthalmia, etc. See hemeralopia.

keratomalacia

softening and necrosis of the cornea associated with vitamin A deficiency.