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keratolysis

   Also found in: Wikipedia 0.01 sec.
keratolysis /ker·a·tol·y·sis/ (ker″ah-tol´ĭ-sis) softening and separation of the stratum corneum of the epidermis.
pitted keratolysis , keratolysis planta´re sulca´tum a tropical disease marked by thickening and deep fissuring of the skin of the soles, occurring during the rainy season.

ker·a·tol·y·sis (kr-tl-ss)
n.
1. The separation or loosening of the horny layer of the epidermis.
2. A skin disease characterized by a periodic shedding of the epidermis.

kera·to·lytic (-t-ltk) adj.

keratolysis
[ker′ətol′ə-sis]
Etymology: Gk, keras + lysis, loosening
the loosening and shedding of the outer layer of the skin, which may occur normally by exfoliation or as a congenital condition in which the skin is shed at periodic intervals. keratolytic, adj.

keratolysis
loosening or separation of the horny layer of the epidermis.

keratolysis
A severe corneal disorder in which the corneal stroma melts, which may result in descemetocele or even perforation. It is believed to be due to an altered epithelial barrier, which results in inflammatory mediators entering the stroma. The condition may occur as a complication of necrotizing scleritis or a severe inflammation of the peripheral cornea, especially in patients with a severe dry eye.


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There is much to whet the appetite of any connoisseur of bizarrely named syndromes, from "toxic sock" syndrome (pitted keratolysis caused by Corynebacterium in athletes) to "hotfoot" syndrome (plantar Pseudomonas folliculitis associated with abrasive swimming pool floors).
 
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