keratocyte


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Related to keratocyte: echinocyte

ker·a·to·cyte

(ker'ă-tō-sīt),
The fibroblastic stromal cell of the cornea.

keratocyte

An erythrocyte formed when haemoglobin denatures—as occurs in alpha-thalassemia or G6PD deficiency—and precipitates—due to oxidation—into clumps (Heinz bodies) that stick to the red cell membrane; the spleen ‘pits out’ a fragment of membrane with precipitated haemoglobin as the cells pass through the sinusoids, hence the term ‘bite’

schistocyte

A fragmented red cell which arises from either an intrinsic increase in cell fragility or due to intravascular rugosities that traumatise cells; schistocytes are a nonspecific finding seen in hemolysis, trauma, prosthetic heart valves, megaloblastic and microangiopathic anaemioccidianhemolytic uremic syndrome, TTP.

ker·a·to·cyte

(ker'ă-tō-sīt)
1. The fibroblastic stromal cell of the cornea.
2. A variety of poikilocyte that owes its abnormal shape to fragmentation occurring as the cell flows through damaged small vessels.
Synonym(s): schistocyte.

keratocyte

1. One of the cells of the main body of the CORNEA.
2. An abnormally-shaped red blood cell bearing horn-like projections. Keratocytes may occur in cases of poisoning or adverse drug reactions in which the red cells are damaged.

corneal corpuscle 

Main cellular element of the corneal stroma. It is a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which may communicate with neighbouring cells. These cells have fibroplastic and phagocytic functions. Syn. corneal fibrocyte; fixed cell; keratocyte.

keratocyte

1. a flattened connective tissue cell lying between the fibrous tissue lamellae which constitute the cornea. The keratocyte has branching processes that communicate with those of other keratocytes.
2. a red blood cell with notches that results in projections that look like horns. Keratocytes occur when fibrin is being deposited within blood vessels as in disseminated intravascular coagulation.
References in periodicals archive ?
Keratocyte phenotype mediates proteoglycan structure: A role for fibroblasts in corneal fibrosis.
Guthoff, "The keratocyte network of human cornea: A three-dimensional study using confocal laser scanning fluorescence microscopy," Cornea, Vol.
Since corneal transparency is the result of a complex organization including regular spacing of the collagen fibrils and extracellular matrix and balanced keratocyte components, high levels of corneal light backscatter may be observed even in the absence of haze or scar.
Concomitant effect of topical ubiquinone Q10 and vitamin E to prevent keratocyte apoptosis after excimer laser photoablation in rabbits," Journal of Refractive Surgery, vol.
Keratocyte death may be attributed to thermal or mechanical damage since photo-ablation increases the local corneal temperature by 10-20 degree Celsius and generates an acoustic shock wave of about 80atm.
After 3 months postoperatively, the rabbits were sacrificed for the immunohistochemical staining study for corneal epithelial marker keratin 3 (K3), corneal keratocyte marker vimentin and conjunctival epithelial marker MUC5AC.
Intraoperative application of mitomycin C is very effective but there are concerns as to the long-term effects of this treatment on keratocyte and endothelial cell density.
Extrapolating these results to the human cornea assumes that dose-dependent keratocyte damage can be expected down to 300[micro]m with the standard 3mW/[cm.
Changes in the balance of the tissue inhibitor of matrix metalloproteinases (TIMPs)-1 and -3 may promote keratocyte apoptosis in keratoconus.
We excluded subjects who wear contact lenses or had a history of contact lens in the past, since wearing contact lenses was reported to cause a decrease in basal epithelial cell density, loss of keratocytes, and endothelial cell damage.