keratoconjunctivitis sicca


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Related to keratoconjunctivitis sicca: Sjogren's syndrome

keratoconjunctivitis

 [ker″ah-to-kon-junk″tĭ-vi´tis]
inflammation of the cornea and conjunctiva.
epidemic keratoconjunctivitis a highly infectious form, commonly with regional lymph node involvement, occurring in epidemics; an adenovirus has been repeatedly isolated from affected patients.
phlyctenular keratoconjunctivitis a form marked by formation of a phlyctenule (small lesion) at the corneal limbus.
keratoconjunctivitis sic´ca a condition marked by hyperemia of the conjunctiva, thickening and drying of the corneal epithelium, and itching and burning of the eye. Called also dry eye.

ker·a·to·con·junc·ti·vi·tis sic·ca

keratoconjunctivitis associated with decreased tears.
See also: Sjögren syndrome.

keratoconjunctivitis sicca

dryness of the cornea caused by a deficiency of tear secretion in which the corneal surface appears dull and rough and the eye feels gritty and irritated. The condition may be associated with erythema multiforme, Sjögren's syndrome, trachoma, and vitamin A deficiency. Methylcellulose artificial tears may give some relief, as can insertion of plugs into the punctae and use of cyclosporine drops.
Dryness of eyes, often due to decreased tear secretion, which occurs in Sjögren syndrome, autoimmune disorders—systemic lupus, rheumatoid arthritis, scleroderma, sarcoidosis—amyloidosis, hypothyroidism, vitamin A deficiency, and in periorbital lymphoproliferative disorders

ker·a·to·con·junc·ti·vi·tis sic·ca

(ker'ă-tō-kŏn-jŭngk'ti-vī'tis sik'ă)
A chronic mucopurulent conjunctivitis, sometimes leading to corneal ulceration and scarring, due to deficit of the aqueous component of tears.
Synonym(s): dry eye syndrome.

keratoconjunctivitis sicca

Dry eye. A state of inadequate wetting and lubrication of the cornea as a result of defective tear production. This results from damage to the tear glands by the same AUTOIMMUNE DISEASE process that causes RHEUMATOID ARTHRITIS, SJOGREN'S SYNDROME, systemic lupus erythematosus and other related conditions. Dry eye is common in all these disorders. There is constant discomfort, foreign-body sensation and sometimes pain and the condition may progress to infection and ulceration of the cornea. Treatment is by the regular use of artificial tears.

ker·a·to·con·junc·ti·vi·tis sic·ca

(ker'ă-tō-kŏn-jŭngk'ti-vī'tis sik'ă)
A chronic mucopurulent conjunctivitis, sometimes leading to corneal ulceration and scarring.
Synonym(s): dry eye syndrome.

keratoconjunctivitis sicca (ker´ə-tōkənjungk´tivī´tis sik´ə),

keratoconjunctivitis

inflammation of the cornea and conjunctiva.

chronic immune-mediated keratoconjunctivitis syndrome
see chronic superficial keratitis.
infectious keratoconjunctivitis
see also infectious bovine kerato conjunctivitis. Caused by Moraxella bovis, Histoplasma capsulatum, Chlamydiae, Mycoplasma spp.
proliferative keratoconjunctivitis
see nodular fasciitis.
keratoconjunctivitis sicca
a condition marked by hyperemia of the conjunctiva, thickening and drying of the corneal epithelium, secondary to quantitative and qualitative deficiencies in the tear film. Deep keratitis and corneal ulceration may occur. Often a tenacious, stringy mucoid discharge accumulates in the conjunctival sac. Called also dry eye.
References in periodicals archive ?
Autoimmunity in the pathogenesis and treatment of keratoconjunctivitis Sicca.
Table 1: Age and sex distribution of subjects Age group Sex Male Female 21-30 12 31-40 15 41-50 4 21 51-60 5 27 61-70 4 9 71-80 3 Table 2: Frequency of ocular manifestations Ocular manifestations Frequency Keratoconjunctivitis sicca 40 Keratitis 3 Scleritis 1 Episcleritis 1 Lenticular opacity (related to RA) 1
The report reviews pipeline therapeutics for Keratoconjunctivitis sicca (Dry Eye) by companies and universities/research institutes based on information derived from company and industry-specific sources
This report provides comprehensive information on the therapeutic development for Keratoconjunctivitis sicca (Dry Eye), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
An Aqueous Calcineurin Inhibitor, SCY-641, Is As Effective As Cyclosporine In The Treatment Of Naturally Occurring Keratoconjunctivitis Sicca In Dogs.
Additionally, Aurinia plans to evaluate its proprietary nanomicellar voclosporin ophthalmic solution (VOS) for the treatment of keratoconjunctivitis sicca (KCS) or dry eye syndrome (DES).
Impression cytology has also been used in the evaluation of ocular surface diseases such as keratoconjunctivitis sicca, [8,9] vitamin A deficiency, [10] cicatricial pemphigoid, [11] atopic disease, [12] superior limbic keratoconjunctivitis and mucopolysaccharidoses, vernal keratoconjunctivitis, [13] and the effect on these of various therapies.
This condition may also be caused by infectious agents like Morexella bovis and sometimes due to allergy, less tear production which are referred to as Infectious bovine Keratoconjunctivitis, allergic keratoconjunctivitis and Keratoconjunctivitis sicca respectively.
The company said RESTASIS is indicated to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca, a type of Chronic Dry Eye disease.
Effects of topical anti-inflammatory agents in a botulinum toxin B-induced mouse model of keratoconjunctivitis sicca.
USPRwire, Sat Mar 14 2015] GlobalData's clinical trial report, "Keratoconjunctivitis sicca (Dry Eye) Global Clinical Trials Review, H1, 2015" provides data on the Keratoconjunctivitis sicca (Dry Eye) clinical trial scenario.