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Keratitis Sicca

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
keratitis sic·ca (sk)
n.
Inflammation of the conjunctiva and cornea of the eye with decreased tears.

Dry Eye Syndrome
Dryness of eyes, often due to decreased tear secretion, which occurs in Sjögren syndrome, autoimmune disorders—systemic lupus, rheumatoid arthritis, scleroderma, sarcoidosis—amyloidosis, hypothyroidism, vitamin A deficiency, and in periorbital lymphoproliferative disorders

keratitis
inflammation of the cornea. Keratitis may be deep, when the infection causing it is carried in the blood or spreads to the cornea from other parts of the eye, or superficial, caused by bacterial or viral infection, trauma, or by allergic reaction. The clinical signs include pain, blepharospasm, ocular discharge, and when chronic, pigmentation.

chronic superficial keratitis
a progressive cellular infiltration with vascularization and eventually pigmentation of the cornea that usually commences at the temporal (lateral) quadrant and advances towards the center. The whole cornea may become involved. It occurs in dogs, particularly German shepherd dogs. The cause is unknown, but exposure to ultraviolet light may be a factor. Cellular infiltrates suggest immune mechanisms are involved in the pathogenesis. Called also CSK, degenerative pannus, Uberreiter's syndrome.
eosinophilic keratitis
a superficial neovascularization and cellular infiltration of the cornea, beginning at the temporal limbus, in adult cats. Eosinophils and plasma cells are found in conjunctival or corneal scrapings and biopsies, and a peripheral eosinophilia is sometimes present. The cause is unknown, but it may be immune-mediated.
exposure keratitis
keratitis resulting from ineffective or incomplete closure of the eyelids with drying of the corneal tear film. Occurs in paralysis of the eyelids, brachycephalic dogs with prominent globes, and cats during ketamine anesthesia. See also lagophthalmos.
herpetic keratitis
herpesvirus infections of the cornea occur in feline and bovine rhinotracheitis infections, and are suspected in dogs. In cats there may be ulcerative keratitis with dendritic ulcers; in cattle conjunctivitis is more common than keratitis.
infectious keratitis
interstitial keratitis
inflammation of the substantia propria, causing dense corneal clouding.
mycotic keratitis
neurotrophic keratitis, neuroparalytic keratitis
a chronic keratopathy resulting from impairment of the sensory (trigeminal) innervation of the cornea.
keratitis nigrum
see corneal sequestrum.
keratitis sicca
superficial diffuse keratitis
see chronic superficial keratitis (above).
superficial pigmentary keratitis
a pigmentation of epithelium and superficial stroma of the cornea, resulting from chronic keratitis from a variety of causes. Seen most commonly in brachycephalic dogs in which the contributing factors are exposure keratitis, distichiasis, irritation from the nasal folds and sometimes keratoconjunctivitis sicca.
superficial punctate keratitis
a keratopathy with discrete opacities of the cornea, without ulceration. Can be caused by irritation.
ulcerative keratitis
see corneal ulcer.


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As was recently announced by Can-Fite (press release of January 30), dry eye symptoms of several RA patients that participated in Can-Fite's Phase IIa study and that also suffered from Keratitis Sicca were significantly improved following treatment with CF101.
As was recently announced by Can-Fite (press release of January 30), dry eye symptoms of several RA patients that participated in Can-Fite's Phase IIa study and that also suffered from Keratitis Sicca were significantly improved following treatment with CF101.
PETACH TIKVA, Israel -- Can-Fite BioPharma (TASE:CFBI) announced today that new clinical data demonstrating activity of CF101 in improving dry eye symptoms in human patients suffering from Keratitis Sicca (know also as Keratoconjunctivitis Sicca) was submitted for presentation in Eular 2006, the Annual European Congress of Rheumatology of the European League Against Rheumatism, to take place in Amsterdam in June, 2006.
 
 
 
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