keratinocyte /ke·rat·i·no·cyte/ (ker-at´in-o-sīt) the epidermal cell that synthesizes keratin, known in its successive stages in the layers of the skin as basal cell, prickle cell, and granular cell.
keratinocyte
ke·rat·i·no·cyte (k -r t n--s t , k r-t n-)n. An epidermal cell that produces keratin. |
keratinocyte
[kerat′inōsīt′]
Etymology: Gk, keras + kytos, cell
an epidermal cell that synthesizes keratin and other proteins and sterols. These cells constitute 95% of the epidermis, being formed from undifferentiated, or basal, cells at the dermal-epidermal junction. Its characteristic intermediate filament protein is cytokeratin. In its various successive stages, keratin forms the prickle cell layer and the granular cell layer, in which the cells become flattened and slowly die to form the final layer, the stratum corneum, which gradually exfoliates.
keratinocyte
the cell of the epidermis that synthesizes keratin, known in its successive stages in the various layers of the skin as basal cell, prickle cell and granular cell.
keratinocyte transit time
the time required for a keratinocyte to move from its origin in the actively dividing cells of the stratum basale to the surface of the epidermis where it is shed. Called also epidermal renewal time. In the normal dog, this is approximately 22 days.
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