keratin pearl


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ker·a·tin pearl

a focus of central keratinization within concentric layers of abnormal squamous cells; seen in squamous cell carcinoma.

ker·a·tin pearl

(ker'ă-tin pĕrl)
A focus of central keratinization within concentric layers of abnormal squamous cells; seen in squamous cell carcinoma.
Synonym(s): epithelial pearl.

keratin

a scleroprotein which is the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix of the enamel of the teeth. Its solution is sometimes used in coating pills when the latter are desired to pass through the stomach unchanged.

keratin cyst
see horn cyst.
keratin pearl
see horn pearls.
keratin tag
see fibrovascular papilloma.
References in periodicals archive ?
NUMEROUS KERATIN PEARLS AND FEW MITOTIC FIGURES WITH CELLULAR AND NUCLEAR PLEOMORPHISM AND HYPERCHROMATISM WEREALSO SEEN, ADIAGNOSIS OF WELL-DIFFERENTIATED SQUAMOUS CELL CARCINOMA WAS GIVE (H&E 20X).
Microphotograph (magnification 40x) showing squamous cell carcinoma with keratin pearls (shown by an arrow).
Microscopically, the tumor was well demarcated from the surrounding tissue and showed coalescing masses of squamous epithelium with abrupt keratinization and keratin pearls.
Histopathological examination of tumor growth revealed hyperkeratinization surrounded by neoplastic squamous cells forming characteristic onion like eosinophilic keratin pearls (cell nests) surrounded by inflammatory cell infilteration (Fig.
intracellular bridges, keratin pearls, and reactivity to markers for high-molecular-weight keratin), it is also made up of melanin-containing cells.
The light microscopic examination revealed squamous cell carcinoma (SCC) as acanthotic squamous epithelium with deep rete pegs, epithelial and keratin pearls, pleomorphism, stromal infiltration and hyperchromatic nuclei (Fig.
Several nests of shadow cells, wet keratin and keratin pearls are present [Figure 3].
1: showing renal tubules, sheets of squamous cells and areas of keratin pearls.

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