juxtacrine

jux·ta·crine

(jŭks'tă-krin),
A mode of hormone action that requires the cell producing the effector to be in direct contact with the cell containing the appropriate receptor.
[L. juxta, close to, + G. krinō, to separate]

juxtacrine

[juks′təkrin]
describing a hormonal relationship in which the secretory cell is adjacent to an effector cell.

jux·ta·crine

(jŭks'tă-krin)
A mode of hormone action that requires the cell producing the effector to be in direct contact with the cell containing the appropriate receptor.
[L. juxta, close to, + G. krinō, to separate]
References in periodicals archive ?
Juxtacrine and paracrine interactions of rat marrow-derived mesenchymal stem cells, muscle-derived satellite cells, and neonatal cardiomyocytes with endothelial cells in angiogenesis dynamics.
They may communicate directly through juxtacrine signaling, over short distances through paracrine signaling and over large distances through endocrine signaling.
The pathways also include an autocrine loop with production and secretion of HER receptor ligands, which may then act in an autocrine, juxtacrine, or paracrine manner.
There is also a need to develop methods for diagnostic typing of the other potential mechanisms of trastuzumab resistance--such as increased expression of the constitutively active truncated form of the HER2 and juxtacrine erbB receptor ligand production, for which preclinical studies have shown promising counter-therapeutic measures to exist.
This suggests the possibility that progression of this disease is associated with TGF-[beta]1 switching from an autocrine/paracrine to a juxtacrine mode of action.