juvenile-onset diabetes


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Type 1 di·a·be·tes

a condition characterized by high blood glucose levels caused by a total lack of insulin. Occurs when the body's immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. Type 1 diabetes develops most often in young people but can appear in adults.

juvenile-onset diabetes, juvenile onset-type diabetes

Type 1 di·a·be·tes

(tīp dī'ă-bē'tēz)
A condition characterized by high blood glucose levels caused by a total lack of insulin. Occurs when the body's immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. Type 1 diabetes develops most often in young people but can appear in adults.
Synonym(s): growth-onset diabetes, juvenile-onset diabetes.

type 1 diabetes mellitus (formerly known as insulin-dependent diabetes mellitus [IDDM] or juvenile-onset diabetes)

acute-onset disease often affecting younger people (peak age of onset = 12 years); caused by autoimmune destruction of insulin-secreting β cells of pancreas islets of Langerhans and insufficient insulin production; undiagnosed patients show polyuria, polydypsia and glycosuria, leading to severe dehydration, marked weight loss and undue fatigability, history of recurrent infections, ketosis and abnormal respiration (hyperventilation, with smell of acetone on the breath) and tendency to ketoacidotic coma; blood tests show uncontrolled hyperglycaemia, dyslipidaemia (high levels of plasma free fatty acids, cholesterol and triglycerides) and ketoacidosis; patients with type 1 diabetes mellitus require lifelong supplementary insulin

Type 1 di·a·be·tes

(tīp dī'ă-bē'tēz)
Condition characterized by high blood glucose levels caused by a total lack of insulin. Occurs when body's immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. Disorder develops most often in young people but can appear in adults.
Synonym(s): juvenile-onset diabetes.
References in periodicals archive ?
Eczema, thyroid problems, allergies, and type I diabetes also turn up in people with IPEX In type I diabetes, also called juvenile-onset diabetes, the immune system destroys insulin-making cells in the pancreas, This autoimmune reaction spurred another research team to investigate whether IPEX patients with type I diabetes are likely to have the FOXP3 mutation.
E[acute accent]Clark had Type 1 diabetes, or juvenile-onset diabetes, since age 6, which progressed into diabetic retinopathy while she was awaiting a kidney transplant seven years ago.
When diabetes struck during childhood earlier, it was routinely assumed to be type 1 or juvenile-onset diabetes.

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