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juvenile xanthogranuloma

   Also found in: Acronyms, Wikipedia 0.01 sec.
xanthogranuloma /xan·tho·gran·u·lo·ma/ (-gran″u-lo´mah) a tumor having histologic characteristics of both granuloma and xanthoma.
juvenile xanthogranuloma  a benign, self-limited disorder of infants and children, with single or multiple yellow, pink, orange, or reddish brown papules or nodules on the scalp, face, proximal limb, or trunk, sometimes with involvement of mucous membranes, viscera, eye, and other organs.

juvenile xanthogranuloma
n.
A skin condition characterized by single or multiple reddish to yellow papules caused by infiltration of the skin by histiocytes and Touton giant cells, usually found in young children. Also called nevoxanthoendothelioma.

juvenile xanthogranuloma,
a skin disorder characterized by groups of yellow, red, or brown papules or nodules on the extensor surfaces of the arms and legs and, in some cases, on the eyeball, meninges, and testes. The lesions typically appear in infancy or early childhood and usually disappear in a few years.

xanthogranuloma, juvenile (JXG) 
A benign proliferation of single or multiple, small yellowish-brown papules or nodules in the skin and the anterior uvea, especially the iris. The condition mainly appears in young children, although it may occur in adults. The lesions consist of dermal infiltration by histiocytes, lymphocytes, eosinophils and Touton giant cells. The skin lesions increase in size and number but eventually regress spontaneously into an atrophic scar, otherwise they may need to be treated by excision or corticosteroid injection. In the eye it is commonly associated with hyphaemia (in the anterior chamber), uveitis and secondary glaucoma with visual loss. Therapy includes topical and systemic corticosteroids. Syn. juvenile nevoxanthoendothelioma.

juvenile xanthogranuloma
Juvenile lipogranuloma, nevoxanthoendothelioma A yellowish tumor of early childhood, involving the face, head, neck, extremities Prognosis Spontaneous involution


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The clinical and microscopic manifestation of SHML should be differentiated from malignant lymphoreticular neoplasias, such as Hodgkin's disease and monocytic leukemia, histiocytosis, rhinoscleroma, tuberculosis, juvenile xanthogranuloma, dermatofibromas, and eosinophilic granuloma, among others.
Only two cases of juvenile xanthogranuloma of the larynx have been previously reported in the literature.
 
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