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Obstructive jaundice is a condition in which there is blockage of the flow of bile from liver to the intestine resulting in overflow of bile and its byproducts into the blood and incomplete excretion of bile from the body.
Predictors of significant jaundice in late preterm infants.
Obstructive jaundice is related to the impairment of bile flow from the liver into the gastrointestinal system due to obstruction in the intra- and extra-hepatic bile ducts.
Neonatal jaundice is a frequent cause of morbidity in newborns worldwide and the most frequent cause of hospitalization and readmission in the initial week of life,1-3 affecting 60% of term and 80% of preterm neonates.
Most studies on neonatal jaundice in Nigeria have dwelt mainly on clinical research concentrating on the medical aetiological factors [2-4,7,8] and on the management of neonatal jaundice by healthcare staff.
Malignant melanoma presenting as obstructive jaundice secondary to metastasis to the Ampulla of Vater.
The present study was designed to compare the mean decrease in serum bilirubin using continuous and intermittent phototherapy techniques for neonatal jaundice.
After identifying clinical jaundice in the newborn, their TSB level is noted following which admission for DSPT or DVET is determined as per neonatal hyperbilirubinemia practice guidelines from AAP-2004 (American Academy of Paediatrics) for newborns--35 weeks and above and from NICE (National Institute for Health and Care Excellence) guidelines for preterm newborns less than 35 weeks.
Causes of pathological jaundice in newborns include increased production of bilirubin, deficiency of hepatic uptake, impaired conjugation of bilirubin, and increased enterohepatic circulation of bilirubin.
Jaundice was the most frequent symptom (96%) followed by abdominal pain (86.
About 60% of term babies and 80% of pre-term infants develop some degree of jaundice during their first week of life.
Obstructive jaundice is a common surgical problem that occurs when there is blockage of the passage of conjugated bilirubin from liver to intestine.