isozyme


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isoenzyme

 [i″so-en´zīm]
any of several forms of an enzyme that all catalyze the same reaction but may differ in reaction rate, inhibition by various substances, electrophoretic mobility, or immunologic properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase, and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.

i·so·en·zyme

(ī'sō-en'zīm),
An enzyme (one of a group) that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation, for example, lactate dehydrogenase, a tetramer composed of varying amounts of α and β subunits (that is, 4α, 3α + 1β, 2α + 2β, 1α + 3β, and 4β).
Synonym(s): isozyme

isozyme

/iso·zyme/ (i´so-zīm) one of the multiple forms in which an enzyme may exist in an organism or in different species, the various forms differing chemically, physically, or immunologically, but catalyzing the same reaction.

isozyme

(ī′sə-zīm′)
n.
An isoenzyme.

i′so·zy′mic adj.

isozyme

See isoenzyme.

i·so·en·zyme

(ī'sō-en'zīm)
One of a group of enzymes that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation.

isozyme

see ISOENZYME.

isozyme

isoenzyme.
References in periodicals archive ?
Four tissues, four extraction buffers and four electrode buffers and nine different enzyme systems were tried for isozyme studies (Table 1)
14) Drugs that inhibit or induce P-450 isozymes can either potentiate or reduce the anticoagulation effect of warfarin, respectively.
Initial isozyme analysis of accession PI 235867 indicated that it was much different from the rest of the accessions in the core subset suggesting that PI 235867 could be a different species.
The characterization by isozymes of the 261 accessions from the Colombian Amazonian Capsicum germplasm collection showed a high variability, as no identical material was found in the phenogram, except for two accessions in C.
In several mollusk species, the genetic distances (D) were estimated from data of isozyme electrophoresis and morphologic differences.
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.
Armstrong, Tyrosine 115 Participates Both in Chemical and Physical Steps of the Catalytic Mechanism of Isozyme 3-3 of Glutathione S-Transferase, J.
Isozyme analysis in conjunction in this same study found high levels of allozyme variation and low levels of heterozygosity, similar to findings for other red oak species (see Hokanson et at.
Hybrid index MLEs for maternal plants based on isozyme data agree well with categories assigned based on morphological and fertility data [ILLUSTRATION FOR FIGURE 1 OMITTED].
Using an anti-myosin-VI antiserum, we showed that an unusually high-mass form of this isozyme is found exclusively in hair bundles (T.
Isozyme analysis is a method whereby specific enzymes or chemicals within the tree can be used as a measuring device to determine genetic diversity.
Somaclonal variation among four Strptomycetes isolates was detected by protein content, pectinase activity and isozyme numbers as well as DNA finger print.