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isotype |
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isotype [ī′sətīp] an antigenic determinant that occurs in all members of a subclass of an immunoglobulin class. An antigenic determinant that is isotypic in one subclass may appear as an allotypic marker in another class. isotype the antigenic variability between related proteins, e.g. between immunoglobulin classes of a single species. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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3] at 4[degrees]C for 15 min with optimal concentrations of antibodies: a) memory helper T cells: CD4-FITC/CD45RO-PE; b) memory cytotoxic T cells: CD8-FITC/CD45RO-PE; c) activated cytotoxic T cells: CD8-FITC/HLADR-PE; d) activated T cells bearing the IL-2 receptor: CD3-FITC/CD25-PE; and e) isotypic controls IgG-FITC and IgG-PE. Mouse IgM preimmune serum was used at the same concentration as the primary antibody to provide an isotypic control. Continued progress in identifying isotypic selective HDAC inhibitors in inflammation, CNS diseases, diabetes, and fungal infections. |
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