isotretinoin


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isotretinoin

 [i″so-tret´ĭ-no-in]
a synthetic form of retinoic acid (13-cis-retinoic acid), used orally to clear cystic and conglobate acne.

i·so·tret·i·noin

(ī'sō-tret'i-noyn),
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

/iso·tret·i·noin/ (i″so-tret´in-o-in) a synthetic form of retinoic acid, used orally to clear cystic and conglobate acne.

isotretinoin

(ī′sō-trĕt′n-oin′)
n.
A synthetic isomer of retinoic acid that inhibits sebaceous gland secretion and is used in the treatment of severe nodular acne. It can cause birth defects if taken during pregnancy.

isotretinoin

[-trətin′ō·in]
an antiacne agent.
indication Subject to significant restrictions, it is prescribed for the treatment of severe cystic acne.
contraindications Pregnancy or sensitivity to the medication or any of its components prohibits its use.
adverse effects A powerful teratogen, young females must be thoroughly educated about the risk of pregnancy and are often placed on birth control pills. The most serious adverse effects to users are epistaxis, cheilitis, conjunctivitis, paresthesia, dizziness, and serum lipid and hematologic disturbances. It may also lower bone mineral density, a consideration for those participating in sports. Some patients become severely depressed or psychotic, which can make them aggressive or suicidal.

isotretinoin

Retinoic acid, 13-cis retinoic acid A retinoid used to treat acne and psoriasis and may ↓ tumor development Side effects Inflammation of skin and mucosa, hepatitis

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

A RETINOID drug used to treat ACNE. The oral preparation is used under strictly controlled conditions to exclude pregnancy because of the known risks to the fetus. Brand names are Roaccutane, and, for external use Isotrex and Isotrexin.

Isotretinoin

A powerful vitamin A derivative used in the treatment of acne. It can promote scarring after skin resurfacing procedures.
Mentioned in: Acne, Skin Resurfacing

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; known human teratogen.

isotretinoin

(ī´sōtret´inoin),
n brand name: Accutane;
drug class: retinoic acid isomer, vitamin A derivative;
action: decreases sebum secretion, improves cystic acne;
uses: severe recalcitrant cystic acne.

isotretinoin

a synthetic form of retinoic acid (13-cis-retinoic acid), used in dermatology for the treatment of disorders of keratinization. It is a potent teratogen.
References in periodicals archive ?
Notable exceptions included dermabrasion and full-face ablative resurfacing; the experts recommended against having such procedures within 6 months of isotretinoin use because of potentially increased risks of adverse events in some patients.
5] Hence, considerable doubt exists in deciding which protocol would give the maximum benefits, so this study has been undertaken to determine and compare the efficacy of the oral isotretinoin in low-dose continuous with low-dose intermittent in the treatment of moderate-to-severe acne vulgaris.
Isotretinoin induced rash, urticaria and angioedema: a case report.
In the absence of large-scale randomized controlled trials of treatments for acne fulminans, the authors said case series and individual reports supported the use of systemic corticosteroids in combination with isotretinoin when treating all forms of the disorder.
I perform a lipid and hepatic panel at baseline and after 2 months of isotretinoin therapy, and if those numbers are okay I don't check them again," she said at the Hawaii Dermatology Seminar provided by the Global Academy for Medical Education/Skin Disease Education Foundation.
The link between isotretinoin and inflammatory bowel disease is not well founded, Dr.
Patient who took oral isotretinoin in the last 12 months were also excluded from the study.
He reported that isotretinoin was very helpful in controlling the condition but the disease returned after discontinuation of treatment.
His history was non-specific except for the use of isotretinoin (20 mg/day initial dose used during the first three months, then increased to 40 mg/day for the following months) six months ago due to acne fulminans.
The introduction of isotretinoin was a major therapeutic advanced which revolutionized the treatment of acne.
Ranbaxy Laboratories and Cipher Pharmaceuticals entered into a licensing agreement in which Ranbaxy would market, sell and distribute the Cipher's isotretinoin capsules in Brazil.