isosorbide


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isosorbide

 [i″so-sor´bīd]
an osmotic diuretic used to reduce intraocular pressure; its dinitrate and mononitrate esters are as coronary vasodilators in treatment of coronary insufficiency and angina pectoris.

i·so·sor·bide

(ī'sō-sōr'bīd),
A compound with diuretic properties prepared by acid dehydration of d-glucitol.

isosorbide

/iso·sor·bide/ (i″so-sor´bīd) an osmotic diuretic used to reduce intraocular pressure; its dinitrate and mononitrate esters are used as coronary vasodilators to treat coronary insufficiency and angina pectoris.

glycerol trinitrate

; GTN; isosorbide potent coronary vasodilator drugs, presented as sublingual spray or tablet, used in the treatment of angina; may cause flushing, headache and postural hypotension; patients develop tolerance over time with resultant reduced therapeutic effect

isosorbide

an osmotic diuretic; the dinitrate of isosorbide is used as a coronary vasodilator.
References in periodicals archive ?
Recently, we have reported (20) a method for the preparation of polyesters for powder coatings combining the chemical recycling of poly(ethylene terephthalate) (PET) with the use of isosorbide and other monomers derived from renewable resources, such as succinic acid and glycerol.
This report covers the present scenario and the growth prospects of the Global Isosorbide market for the period 2015-2019.
Resins and polymers emerged as the largest end-use industry for isosorbide and accounted for over 60% of the global demand in 2012.
First, pure poly(L-lactide) for all polymerization methods was synthesized, and this process is followed by the synthesis of three polymers, with isosorbide in the middle of polymer chains with desired molecular weights of 20,000, 40,000, and 60,000 g [mol.
Supplementary analysis has been carried out on sorbitol potential as a platform chemical for the production of polyols (ethylene glycols, propylene glycols and glycerols) and isosorbides.
The 80 rats were randomly divided into 6 groups: normal control (Control), sham operation (Sham), injured (AMI), PE low dose (AMI + PE-L), PE high dose (AMI + PE-H) and isosorbide dinitrate positive control (AMI + isosorbide).
Overdoses of propafenone HCI, isosorbide mononitrate, morphine sulfate and dextroamphetamine sulfate can have serious or life-threatening consequences," says a company statement.
Augmentation of the vasodilatory effects of isosorbide dinitrate by phosphodiesterase inhibitors (e.
These A-HeFT data show isosorbide dinitrate-hydralazine (BiDil) lowered blood pressure only in patients with normal or elevated baseline systolic blood pressure.
BilDil is a combination of two older, generic drugs: hydralazine, a high blood pressure medicine; and isosorbide nitrate, which relaxes arteries' muscular walls, allowing more blood flow through arteries narrowed by heart disease.
The fixed-dose combination of isosorbide dinitrate and hydralazine is the first product approved specifically for treating patients in a specific racial group.