Isoschizomer | definition of isoschizomer by Medical dictionary
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A restriction endonuclease from different organisms that recognizes and hydrolyzes at the same DNA sequence.
[jiso- + G. schizō to split, + -mer]
isoschizomer a RESTRICTION ENZYME that recognizes the same recognition sequence for cleavage of the DNA as other restriction enzymes.
References in periodicals archive
In both methods, the DNA was digested by HpaII (a methylation-sensitive enzyme) and MspI (a methylation-insensitive isoschizomer
enzyme) and analyzed by real-time PCR amplification.
profiling of cytosine methylation: the HELP assay.
16) that incorporated a hot-start PCR and isoschizomer
of the restriction enzyme for more efficient digestion.
The amplified samples were checked for purity and quantity on a standard agarose gel (10 g/L) and digested with Cfol, an isoschizomer