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isogenic |
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isogenic /iso·gen·ic/ (-jen´ik) syngeneic. isogenic (ī´sōjen´ik), adj originating from a common source; possessing the same genetic composition. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| To better study the impact of rpoB mutation on meningococcal virulence we constructed an isogenic mutant strain, NM05-08, by transforming the susceptible isolate LNP21362 with a PCR-amplified fragment from a resistant isolate (LNP22330), as previously described (6). The degree of methylation and corresponding level of ectopic Agouti expression vary stochastically among individual isogenic [A. Moreover, it allows the production of hESCs in a totally isogenic system where the conditioned medium is produced by derivatives of the hESCs themselves. |
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