isoflavan

isoflavan

estrogenic substance in plants. Called also equol.
Mentioned in ?
References in periodicals archive ?
Glabridin, an isoflavan from licorice root, inhibits inducible nitric-oxide synthase expression and improves survival of mice in experimental model of septic shock.
Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway.
Glabridin, An isoflavan from licorice root, down-regulates iNOS expression and activity under high glucose stress and inflammation.
In vitro and in vivo, two natural compounds derived from licorice root demonstrated estrogen like activity on vascular tissues: glabrene, an isoflavene, behaved as a partial agonist/antagonist of estradiol while glabridin, the major isoflavan, demonstrated only estrogenic activity (Somjen 2004b).
Licorice root extract, as well as its major isoflavan glabridin, is a potent antioxidant against LDL oxidation in mice and humans (Rosenblat et al.
The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9.