islets of Langerhans


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Related to islets of Langerhans: insulin, pancreas, somatostatin

is·lets of Lan·ger·hans

(lahng'ĕr-hahnz),
cellular masses consisting of several to several hundred cells lying in the interstitial tissue of the pancreas; they are composed of five different cell types that make up the endocrine portion of the pancreas and are the sources of insulin, glucagon, somatostatin, pancreatic polypeptide, and gastrin.

islets of Langerhans

(ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

islets of Langerhans

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses varying from a few to hundreds of cells lying in the interstitial tissue of the pancreas; they are the source of insulin and glucagon.

Islets of Langerhans

INSULIN secreting collections of cells lying in the INTERSTITIAL tissue of the PANCREAS. (Paul Langerhans, 1847–1888, German medical student, later anatomy professor).

islets of Langerhans

groups of cells found scattered in the pancreas of jawed vertebrates.

Islets of Langerhans

Special structures in the pancreas responsible for insulin secretion among other functions. They are named for Paul Langerhans, the German researcher who first identified them in 1869.

Langerhans,

Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans

islets of Langerhans

pancreatic secretory cells; alpha cells release glucagons and beta cells release insulin

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses consisting of several to several hundred cells lying in interstitial pancreatic tissue.
References in periodicals archive ?
Keywords: Islets of langerhans, Pancreatic lesions, Sodium cyclamate.
The endocrine role of the pancreas in metabolism, and indeed the existence of insulin, was not further clarified until 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs.
The greatest obstacle to studying the exact workings of the Islets of Langerhans and how they adapt to individual conditions is their relative inaccessibility, in that they lie deeply embedded in and are distributed throughout the tissue.
Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts.
Insulin is an essential polypeptide hormone produced under conditions of feeding by the beta cells of the pancreatic islets of Langerhans.
It involves transplanting healthy insulin-producing cells, called islets of Langerhans, into a diabetes Type I sufferer.
8) The cytologic distribution and percentages were similar to those of the normal islets of Langerhans.
These portions, scattered through the pancreatic background, were the Islets of Langerhans (see 1869).
The group has developed what they describe as the most accurate test yet made to identify persons at risk for contracting type 1 diabetes, which is associated with an onset in childhood and the absence of production of insulin by the pancreatic islets of Langerhans.
The patent provides protection to a specific cell line derived from human pancreatic tissues that gives rise to structures comparable to the Islets of Langerhans (beta islets).
The starting point of the research was recognition that in healthy people, insulin, which regulates blood glucose levels and helps convert glucose from carbohydrates into energy, is produced in the pancreas by aggregates of endocrine cells called islets of Langerhans, which normally secrete insulin in pulses.