islets of Langerhans


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Related to islets of Langerhans: insulin, pancreas, somatostatin

is·lets of Lan·ger·hans

(lahng'ĕr-hahnz),
cellular masses consisting of several to several hundred cells lying in the interstitial tissue of the pancreas; they are composed of five different cell types that make up the endocrine portion of the pancreas and are the sources of insulin, glucagon, somatostatin, pancreatic polypeptide, and gastrin.

islets of Langerhans

(ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

islets of Langerhans

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses varying from a few to hundreds of cells lying in the interstitial tissue of the pancreas; they are the source of insulin and glucagon.

Islets of Langerhans

INSULIN secreting collections of cells lying in the INTERSTITIAL tissue of the PANCREAS. (Paul Langerhans, 1847–1888, German medical student, later anatomy professor).

islets of Langerhans

groups of cells found scattered in the pancreas of jawed vertebrates.

Islets of Langerhans

Special structures in the pancreas responsible for insulin secretion among other functions. They are named for Paul Langerhans, the German researcher who first identified them in 1869.

Langerhans,

Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans

islets of Langerhans

pancreatic secretory cells; alpha cells release glucagons and beta cells release insulin

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses consisting of several to several hundred cells lying in interstitial pancreatic tissue.
References in periodicals archive ?
The greatest obstacle to studying the exact workings of the Islets of Langerhans and how they adapt to individual conditions is their relative inaccessibility, in that they lie deeply embedded in and are distributed throughout the tissue.
Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts.
Isolated islets of Langerhans were loaded with 5 [micro]M fura 2-acetoxymethyl ester for at least 1 hr at room temperature.
Islet amyloid is a form of local amyloidosis, since it is confined to the islets of Langerhans.
To measure insulin release from isolated islets, mice were killed by cervical dislocation, and pancreatic islets of Langerhans were isolated by collagenase digestion as described previously (Morimoto et al.
Lacy, one of the true pioneers in islet cell transplantation, is recognized for developing techniques to isolate and culture clusters of cells know as the islets of langerhans found throughout the pancreas.
After removing extraneous proteins and immune cells from these so-called islets of Langerhans, physicians injected them into diabetes patients via a large vein in the liver.
4] This aberrant pancreas is composed of pancreatic acini, ducts lined by columnar cells, and islets of Langerhans, and it is thought to represent a developmental anomaly.
The endocrine cells appeared as bud-like clusters resembling the islets of Langerhans and included the major islet cell types that produce the hormones insulin, glucagon and somatostatin.
Last month, JDRF awarded Beta-O2 a grant to fund half of the $1M, two-year, open label, pilot investigation which will evaluate the safety and efficacy of implanting the EAir macro-encapsulation with human islets of Langerhans.
Alpha and beta cells are grouped in areas of the pancreas called the islets of Langerhans.