islet


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Related to islet: islet cells

islet

 [i´let]
an island.
i's of Langerhans (pancreatic i's) irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
Walthard's i's microscopic inclusions of the ovarian germinal epithelium, which have been implicated in the development of Brenner tumors.

is·let

(ī'let),
A small island.

islet

/is·let/ (-lit) an island.
islets of Langerhans  irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin; the delta cells, which secrete somatostatin; and the PP (or F ) cells, which secrete pancreatic polypeptide. Degeneration of the beta cells is one of the causes of diabetes mellitus.

islet

[ī′lət]
Etymology: MFr, islette, little island
a cluster of cells or an isolated piece of tissue. Also called island.

is·let

(ī'lĕt)
A small island.

islet

an island.

islet cell
one of the cells making up the islet of Langerhans.
islet cell neoplasia
occur mostly in old dogs and morphologically they occur as adenomas or adenocarcinomas. Functionally they appear only in the form of hyperinsulinism and hypoglycemia. Rarely there are gastrin-secreting tumors causing a zollinger-ellison syndrome.
i's of Langerhans
irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus; and the delta cells, which secrete somatostatin.
pancreatic islet
see islets of Langerhans (above).
References in classic literature ?
A few days afterwards, when not far distant from the Abrolhos Islets, my; attention was called to a reddish-brown appearance in the sea.
Islet transplantation 2003: Questions about its future.
Preliminary research at Cedars-Sinai Medical Center in California shows that a protein in the body called GLP-1 helps prevent insulin-producing islet cells in the pancreas from dying.
Islet transplantations have taken place but recipients need strong anti- rejection drugs which can produce harsh side-effects.
This new patent, entitled Methods of Culturing and Encapsulating Pancreatic Islet Cells, covers processes to effectively culture and transplant functional and viable islet cells, the major insulin-secreting cells, into people with insulin-dependent (type 1) diabetes mellitus.
Kinmen County announced Tuesday that the Jiangong Islet, or Jiangongyu, will be closed for reconstruction from 20 December through March 8 next year, reported CNA.
Background: Improving islet graft revascularization has become a crucial task for prolonging islet graft survival.
For the quantification of intra islet capillaries, forty eight sections (8 per group) stained immunohistochemically using BS1 lectin were used.
In fact, GLP1 is not only able to (i) increase the insulin gene expression and insulin biosynthesis, but also to (ii) induce the replication of islet cells and promotes islet-cell neogenesis and (iii) protect islets cells from apoptosis.
Most patients require regular insulin injections, but some need surgical intervention--either a pancreas transplant or an islet cell transplant, in which insulin-producing islet cells from a donor pancreas are infused into the liver.
123 EMERGING NEW DIABETES TREATMENT STRATEGIES: BETATROPHIN VERSUS ISLET CELL TRANSPLANTATION
Biopharmaceutical company Islet Sciences (Other OTC:ISLT) disclosed on Monday the addition of Dr William Wilkison to its board of directors.