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ischemic penumbra

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ischemic penumbra,
an area of moderately ischemic brain tissue surrounding an area of more severe ischemia. Theoretically, blood flow to this area may be enhanced in order to prevent the spread of a cerebral infarction.

ischemic penumbra
Neurology An ischemic zone in the brain at risk of infarction, which lies in a 'no-man's land' between a zone of low blood flow–< 25 ml/100 mg brain tissue/min and a zone where brain tissue is undergoing necrosis–flow–< 8 ml/100 mg/min. Cf Hemorrhagic stroke.


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Specific topics include: burden of stroke and risk factors, implications of strike pathophysiology and the ischemic penumbra, neuroplasticity and neurorecovery, classification of stroke subtypes, neuroimaging, management of acute ischemic stroke, and medical treatment for secondary stroke prevention.
The ischemic penumbra represents part of the hypoperfused region associated with focal brain ischemia that potentially can be salvaged by timely intervention.
4) The presence and extent of the ischemic penumbra is time-dependent, but especially patient-dependent.
 
 
 
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