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iron transport |
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iron transport, the process whereby iron is carried from the intestinal mucosa to sites of use and storage. Iron binds with transferrin and shuttles to storage and utilization sites. Transferrin becomes attached to exogenous iron that enters through the intestinal villi or that reenters the plasma from the sinusoids of the spleen. The iron is then released to the normoblasts, and the transferrin is freed for additional transport functions that may involve iron stored as ferritin or hemosiderin. See also hemosiderosis, iron metabolism, transferrin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| The 14 review papers presented here survey all relevant aspects, beginning with comparative genomics and clinical relevance, and covering adherence, flagella and pili, motility and chemotaxis, iron transport and signaling, and quorum sensing, among other topics. Parameters of iron status used in iron assessment Iron status stored iron Transport iron (ferritin) (transferrin) Iron-deficiency anemia Low Low Iron depletion Low Normal Normal iron status Normal Normal Iron overload High High Iron status Functional iron (haemoglobin) Iron-deficiency anemia Low Iron depletion Normal Normal iron status Normal Iron overload Normal Table 2. 14,15) In the duodenum, dietary free iron is enzymatically reduced from the ferric (+3) form to ferrous (+2) iron and taken up from the intestinal lumen into the enterocytes by the iron transport protein, divalent metal transporter 1 (DMT1). |
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