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irinotecan |
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irinotecan /iri·no·te·can/ (i″rĭ-no-te´kan) a DNA topoisomerase inhibitor used as the hydrochloride salt as an antineoplastic in the treatment of colorectal carcinoma. irinotecan, an antineoplastic hormone. indication It is used to treat metastatic carcinoma of the colon or rectum. contraindications Pregnancy and known hypersensitivity to this drug prohibit its use. adverse effects Life-threatening effects include leukopenia, anemia, and neutropenia. Other adverse effects include fever, headache, chills, dizziness, diarrhea, nausea, vomiting, anorexia, constipation, cramps, flatus, stomatitis, dyspepsia, site irritation, rash, sweating, dyspnea, increased cough, rhinitis, vasodilation, edema, asthenia, and weight loss. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Encapsulating irinotecan into a liposome developed by Terumo, the new agent will be able to sustain its effectiveness and improve its concentration in cancer tissues while reducing side effects. In these people, irinotecan induces a sharp drop in white blood cell count, a side effect that opens the door to infections. including, Amifostine, Carboplatin USP, Cisplatin USP, Doxorubicin HCl USP, Epirubicin HCl EP, Etoposide USP, Fludarabine Phosphate, Gemcitabine HCl USP, Ifosfamide USP, Irinotecan HCl 3H2O, Mitoxantrone HCl USP/PhEur and Thiotepa USP. |
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