inulin clearance

clearance /clear·ance/ (klēr´ans)

1. the act of clearing.

2. a quantitative measure of the rate at which a substance is removed from the blood, as by the kidneys, the liver, or hemodialysis; the volume of plasma cleared per unit time. Symbol C.

3. the space between opposed structures.

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blood-urea clearance  urea c.

creatinine clearance  the volume of plasma cleared of creatinine after parenteral administration of a specified amount of the substance.

inulin clearance  an expression of the renal efficiency in eliminating inulin from the blood.

mucociliary clearance  the clearance of mucus and other materials from the airways by the cilia of the epithelial cells.

urea clearance  the volume of the blood cleared of urea per minute by either renal clearance or hemodialysis.

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inulin clearance

n.

A method for determining the rate of filtration in the renal glomeruli, since inulin is completely filterable through them and is neither excreted nor reabsorbed by the renal tubules.

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inulin clearance,

a test of the rate of filtration of a starch, inulin, in the glomerulus of the kidney. Inulin is given by mouth, and the glomerular filtration rate can be estimated from the amount of inulin that appears in the urine. The clearance rate of inulin in urine for adults with normal renal function is 100 to 150 mL/min.

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clearance

the act of clearing; it is a primary pharmacokinetic parameter which describes irreversible removal of a drug from the body by all processes and is made up of renal clearance and metabolic clearance.

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blood-urea clearance

the volume of the blood cleared of urea per minute by renal elimination.

Bromsulphalein clearance

see sulfobromophthalein clearance test.

creatinine clearance

see creatinine.

inulin clearance

see inulin clearance.

clearance time

the time required for a drug to be eliminated after administration. Eliminated means to the point where it can no longer be detected. Of most importance in avoiding drug residues in food animals and charges of doping in sports animals.

urea clearance

blood-urea clearance.

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inulin

a starch occurring in the rhizome of certain plants, which on hydrolysis yields fructose. It is used to measure glomerular function in tests of renal function.

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inulin clearance

an expression of the renal efficiency in eliminating inulin from the blood, a measure of glomerular function.