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intron
(redirected from intronic)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.18 sec.
intron /in·tron/ (in´tron) a noncoding sequence between two coding sequences within a gene, processed out in the formation of mature mRNA.
in·tron (ntrn)
n.
A segment of a gene situated between exons that does not function in coding for protein synthesis.

intron
[in′tron]
Etymology: L, intra, within, regin, region
a sequence of nucleotides in eukaryotic DNA that does not code for amino acids and interrupts the coding sequence of a gene. Some genes contain numerous long introns. Compare exon.

intron
untranslated, intervening sequences that are interspersed between coding sequences of a particular gene of almost all eukaryocytic genes and which are excised from the primary RNA transcript to yield mRNA.

intron-exon junction
introns are removed by the catalytic action of small nuclear riboproteins (snRNPs) which bind to special recognition sequences at the 5,(donor junction) and 3,(receptor junction) to form a complex called a spliceosome.


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? Mentioned in ? References in periodicals archive
 
The tau gene in progressive supranuclear palsy: exclusion of mutations in coding exons and exon 10 splice sites, and identification of a new intronic variant of the disease-associated H1 haplotype in Italian cases.
Recent work has demonstrated that intronic mutations can have functional consequences in some genes such as p53 (Lehman et al.
5 kb downstream of the last exon, and a significant amount of intronic sequence have been examined.
 
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