intron


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in·tron

(in'tron),
A portion of DNA that lies between two exons, is transcribed into RNA, but does not appear in that mRNA after maturation because the intron is removed and the exons spliced together, and so is not expressed (as protein) in protein synthesis. By customary usage, the term is extended to the corresponding regions in the primary transcript of mRNA before maturation.
[inter- + -on]

intron

/in·tron/ (in´tron) a noncoding sequence between two coding sequences within a gene, processed out in the formation of mature mRNA.

intron

(ĭn′trŏn)
n.
A segment of a gene situated between exons that is removed before translation of messenger RNA and does not function in coding for protein synthesis.

intron

[in′tron]
Etymology: L, intra, within, regin, region
a sequence of nucleotides in eukaryotic DNA that does not code for amino acids and interrupts the coding sequence of a gene. Some genes contain numerous long introns. Compare exon.

in·tron

(in'tron)
A portion of DNA that lies between two exons, is transcribed into RNA, but does not appear in that RNA after maturation, and so is not expressed (as protein) in protein synthesis.

intron

A non-coding segment of a DISCONTINUOUS GENE. Introns are lengths of DNA interposed between coding segments (EXONS) in a gene and are transcribed into MESSENGER RNA but are then removed from the transcript and the exons spliced together. Introns do not contain biological information.

intron

or (‘in’ for intervening) - an intervening nucleotide sequence in an INTERRUPTED split gene. Such sequences are transcribed into primary RNA transcripts, but then excised from the RNA, leaving behind the EXON sequences for the functional gene product. See RNA PROCESSING, RNA SPLICING.

intron

untranslated, intervening sequences that are interspersed between coding sequences of a particular gene of almost all eukaryocytic genes and which are excised from the primary RNA transcript to yield mRNA.

intron-exon junction
introns are removed by the catalytic action of small nuclear riboproteins (snRNPs) which bind to special recognition sequences at the 5,(donor junction) and 3,(receptor junction) to form a complex called a spliceosome.
References in periodicals archive ?
The 281-bp difference in the intron 20 between the European pigs and the Chinese pigs was due to an inserted 276-bp element near the beginning of the intron and GACTT insertion at nucleotides 401-405 of the 514 bp intron 20 in the European pigs (Figure 1B).
Because all novel alleles were found to exclusively harbor intronic polymorphisms, we sought to characterize HLA variability by genomic feature (UTR, intron, and exon) to determine whether or not intronic variations are more or less common than polymorphisms within other regions of the HLA genes.
The six distinct causative mutations detected in this study and those found in seven patients from a previous work (11) [3 intron 22 inversions, 2 missense (p.
The primers were intended to amplify seven fragments corresponding to all the four exons (full coding regions) and three introns (partial noncoding regions) of [beta]2M gene in buffalo.
Human genes are composed of exons and interrupted by introns that must be removed by splicing to create a translatable mRNA.
Oranjewoud Realisatie is the first company that was certified by INTRON.
1 that possibly insertion of first intron (809 bp) and second exon (707 bp) has taken place in humans and similarly insertion of first intron (809 bp) and second exon (704 bp) has taken place in chimps some 6-10 million years ago, i.
In this study, we investigated the role of the intron F G79A polymorphism of the PZ gene and its effects on expression of the plasma PZ levels in pediatric stroke patients.
INTRON A (Interferon alfa-2b, recombinant) for Injection is contraindicated in patients with hypersensitivity to INTRON A or any component of the product, autoimmune hepatitis, and decompensated liver disease.
15) Finally, one of the RNA components of the spliceosome (snRNA U5) can functionally substitute for a particular portion of the group II intron (ID3 subdomain stem-loop).