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Related to intrinsic pathway: Extrinsic pathway
intrinsic pathwayHematology An arm of the coagulation cascade, initiated by negatively charged surfaces–contact factors–eg, sulfatide micelles, kaolin which bind factor XII and HMW kininogen–HMWK; HMWK binds prekallikrein and factor XI, activating the latter; XIa then activates IX which in turn activates factor X, initiating the common pathway. See Common pathway, Extrinsic pathway.
One of three pathways in the coagulation cascade.
Mentioned in: Partial Thromboplastin Time