intravascular


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intravascular

 [in″trah-vas´ku-lar]
within a vessel or vessels.

in·tra·vas·cu·lar

(in'tră-vas'kyū-lăr),
Within the blood vessels or lymphatics.

intravascular

/in·tra·vas·cu·lar/ (in″trah-vas´ku-lar) within a vessel.

intravascular

(ĭn′trə-văs′kyə-lər)
adj.
Within blood vessels or a blood vessel.

in′tra·vas′cu·lar·ly adv.

intravascular

[-vas′kyələr]
Etymology: L, intra + vasculum, little vessel
pertaining to the inside of a blood vessel.

intravascular

adjective Within a blood vessel.

hemoglobinuria

Hematology The presence of Hb in the urine which, if of sufficient quantity, colors urine, the intensity of which directly correlates with the quantity of Hb. See Paroxysmal cold hemoglobinuria, Paroxysmal nocturnal hemoglobinuria.
hemolysis Destruction or lysis of RBCs
Hemolysis
Intracorpuscular hemolysis
•  Membrane defects, eg hereditary elliptocytosis, spherocytosis, stomatocytosis and paroxysmal nocturnal hemoglobinuria
•  Metabolic defects, eg G6PD, pyruvate kinase deficiency
•  Abnormal Hbs see Hemoglobin.
Extracorpuscular hemolysis
1º immune reactions, eg autoimmune hemolytic anemia
2º immune reactions, due to
• Infections, eg Bartonella, Clostridia, malaria, sepsis
• Neoplasia, eg lymphoma, leukemias
• Drug reactions due to the 'Innocent bystander' phenomenon (drug-antibody complex activates complement, causing intravascular hemolysis, eg quinidine), hapten-mediated —a protein-bound drug attaches to the red cell membrane, eliciting an immune response when the hapten-protein complex is recognized as foreign, evoking an immune response, eg penicillin acting as a hapten
• Induction of autoimmunity by RBC antigen alterations, eg Rh antigen
Physical, eg thermal, concentrated glycerol due to inadequate washing of frozen blood, bladder irrigation, cardiac valves
Extravascular Less severe, IgG-mediated and does not activate complement, eg Rh, Kell, Duffy Laboratory ↓ haptoglobin, ↓ T1/2 of circulating RBCs, ↑ indirect BR as liver capacity to conjugate BR–ergo direct BR is overwhelmed by massive hemolysis, ↑ LDH, Hb in blood and urine, hemosiderinuria, MetHb and metalbumin, ↑ urobilinogen in urine and feces, ↑ in acid phosphatase, K+, and prostatic acid phosphatase Clin Chem 1992; 38:575; peripheral smears demonstrate anisocytosis, polychromatophilia, nucleated RBCs, basophilic stippling; immune hemolysis is suggested by spherocytes NEJM 2000; 342:722cpc
Intravascular More severe, IgM-mediated and requires complement activation, eg ABO blood groups Laboratory ↑ free Hb  Note: Clinically significant hemolysis is usually detected by hemagglutination, less commonly by hemolysis per se, which detects anti-P,
-P1, -PP1Pk, -Jka, -Lea, occasionally also anti-Leb and -Vel

intravascular

Within a blood vessels within the lymphatics.

in·tra·vas·cu·lar

(IV) (in'tră-vas'kyū-lăr)
Within the blood vessels or lymphatics.

intravascular (in´trəvas´kūlur),

adj within a blood vessel.

intravascular

within a vessel or vessels.

disseminated intravascular coagulation
see disseminated intravascular coagulation.
intravascular fluid
that part of the total body fluid that is within the vascular system.
intravascular space
the space occupied by the blood.
References in periodicals archive ?
On contrast enhanced CT scan, intravascular fibroids are seen as hypodense filling defects in the vessel, inferior vena cava and right atrium7.
El proposito de la dosis de prueba en bloqueos regionales es descartar la puncion inadvertida intravascular, mientras que en bloqueos epidurales es descartar su presencia de la aguja o el cateter tanto en el espacio subaracnoideo e intravascular.
To assess the fibrinolytic activity (using D-dimer assay) in clinically diagnosed cases of Acute disseminated intravascular coagulation.
Separate, previous trials using intravascular ultrasound have shown that high-dose statin therapy is more effective than moderate- or low-dose regimens to halt progression of atherosclerosis, he added.
Intravase is a sterile, GMP-grade secondary reagent used with the Celution System to prepare the Celution cell output for safe intravascular delivery.
Intravascular large B-cell lymphoma has no specific chromosomal alterations, but many abnormalities reported in other B-cell lymphomas may be seen in IVLBCL.
InfraReDx's LipiScan IVUS Coronary Imaging System is the first and only available catheter to combine both near-infrared spectroscopy (NIR) and intravascular ultrasound (IVUS) technologies to both visualize and characterize the intracoronary lipid core plaques (LCP) suspected of causing the majority of heart attacks.
Clinically, intravascular papillary endothelial hyperplasia (IPEH) often presents as a subcutaneous or submucous red-blue mass.
Given the imaging findings and intravascular hemolysis caused by a dysfunctional mitral valve, the most likely cause for the renal MRI findings was renal hemosiderosis.
1-3) The CDC found that the incidence of CRBSIs varies considerably by type of intravascular catheter, frequency of intravascular catheter manipulation, and patient-related factors.
A The Scientific Subcommittee (SSC) on Disseminated Intravascular Coagulation of the International Society on Thrombosis and Haemostasis (ISTH) published a definition of DIC as well as clinical and laboratory criteria for diagnosis in the December 2001 issue of Thrombosis and Haemostasis.
Recent reports suggest that both the nature of intravascular foreign objects and new tools with sophisticated techniques available to retrieve them, have changed substantially in the past decade.

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