No Mortality or Toxicity Noted With CryoStor Deployed as Vehicle Solution for Cells and Placebo in Direct Intramyocardial
delivery of the CorMatrix to mechanically stabilize, repair and recover infarcted regions of the heart could provide myocardial recovery for these heart failure patients.
small arterioles showed significant atherosclerotic changes in model group.
This has been recently confirmed by experimental studies demonstrating that intravenous or intramyocardial
FGF-23 administration resulted in the induction of hypertrophy of rat cardiomyocytes and in the development of left ventricular hypertrophy in the animal model (24).
Left-ventricular shape determines intramyocardial
2ml alginate-hydrogel (or normal saline) was administered by 6 intramyocardial
injections around the ischemic area, identified by its pale color and decreased systolic motion.
In an afebrile patient with no history of prosthetic valves or materials isolated intramyocardial
abscess formation is very unusual, despite the relatively high prevalence of bacteremia.
Regeneration of infarcted myocardium by intramyocardial
implantation of ex vivo transforming growth factor-beta-preprogrammed bone marrow stem cells.
It was then sewn in a side-to-side fashion to the large diagonal ramus, and then it was coursed over and was sewn end-to-side to the intramyocardial
portion of the left anterior descending coronary artery.
A promising concept currently under investigation is intramyocardial
injection of high-water content, polymeric biomaterial gels (e.
short- and long-axis T1-weighted images may be added to investigate the distribution of intramyocardial
Cardiogenesis has also developed the PHOENIX Combination Delivery System, which is designed to combine the intramyocardial
delivery of biologic materials with TMR.