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intramucosal carcinoma

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intramucosal carcinoma
Oncology A high-grade/severe dysplasia–CIS of the GI mucosa, which extends to the lamina propria


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This term encompasses cases in which the entire polyp head is replaced by carcinoma and adenomas with focal malignancy, but the definition excludes adenomas with high-grade dysplasia (intraepithelial carcinoma) or intramucosal carcinoma (invasive carcinoma limited to the lamina propria or invading no deeper than the muscularis mucosae), because these polyps possess negligible biologic potential for metastasis (see Tis in note N).
Protocol for the Examination of Specimens From Patients With Primary ... by Mary Kay Washington and Jordan Berlin and Philip A Branton and Lawrence J Burgart and David K Carter / Archives of Pathology & Laboratory Medicine
5%-3% of the cases), usually those measuring greater than 2 cm, show dysplasia or even intramucosal carcinoma.
Gastric Polyps: Classification and Management by Do Youn Park and Gregory Y Lauwers / Archives of Pathology & Laboratory Medicine
Tis Intramucosal carcinoma (invasion of lamina propria)
Protocol for the Examination of Specimens From Patients With Invasive ... by Joseph Misdraji and Esther Oliva and John R Goldblum and Gregory Y Lauwers and Et al / Archives of Pathology & Laboratory Medicine
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