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intracrine

   Also found in: Wikipedia 0.26 sec.
intracrine /in·tra·crine/ (in´trah-krin) denoting a type of hormone function in which a regulatory factor acts within the cell that synthesizes it by binding to intracellular receptors.
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Targeted disruption of the mouse estrogen sulfotransferase gene reveals a role of estrogen metabolism in intracrine and paracrine estrogen regulation.
Crystallographic analysis of a hydroxylated polychlorinated biphenyl ... by Negishi, Masahiko / Environmental Health Perspectives
The modification is important because the intracrine 17[beta]-estradiol production in peripheral tissues, by aromatization of androgens, is the only 17[beta]-estradiol source in men and postmenopausal women.
Dual effects of phytoestrogens result in U-shaped dose-response ... by Leffers, Henrik / Environmental Health Perspectives
Role of 17-beta-hydroxysteroid dehydrogenase type 1 in endocrine and intracrine estradiol synthesis.
Genistein: Does It Prevent or Promote Breast Cancer? by Hilakivi-Clarke, Leena / Environmental Health Perspectives
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