intracarotid infusion

intracarotid infusion

Therapeutics The introduction of fluids and drugs directly into the carotid artery, ergo the brain without passing through the liver
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The early and late effects of intracarotid infusion of the drug vehicle (HCD) are summarized in Table 1.
However, intracarotid infusion of 17-[beta]-estradiol failed to increase cerebral blood flow in rabbits (Littleton-Kearney et al.
For this purpose, we continuously recorded cerebrocortical perfusion by laser-Doppler flowmetry in anesthetized rats receiving intracarotid infusions (1 mg/kg) of one of the following estrogenic compounds: biochanin A, daidzein, genistein or zearalanone.
While the patient is under general anesthesia, osmotic opening or disruption is achieved by a 30-second intracarotid infusion of mannitol.
A continuous 30-second intracarotid infusion of a hypertonic solution (mannitol) causes osmotic shrinkage of the endothelial cells with resultant opening of the tight junctions, therefore allowing the large-molecular-weight chemotherapeutic agents into the brain tissue.
Histological changes in brain tissue and vasculature after intracarotid infusion of organic solvents in rats.