interstitial fluid

fluid /flu·id/ (floo´id)

1. a liquid or gas; any liquid of the body.

2. composed of molecules which freely change their relative positions without separation of the mass.

---

amniotic fluid  the liquid within the amnion that bathes the developing fetus and protects it from mechanical injury.

cerebrospinal fluid  (CSF) the fluid contained within the ventricles of the brain, the subarachnoid space, and the central canal of the spinal cord.

follicular fluid  the fluid in a developing ovarian follicle.

interstitial fluid  the extracellular fluid bathing most tissues, excluding the fluid within the lymph and blood vessels.

intracellular fluid  the portion of the total body water with its dissolved solutes which are within the cell membranes.

prostatic fluid  the secretion of the prostate gland, which contributes to formation of the semen.

Scarpa's fluid  endolymph.

seminal fluid  semen.

synovial fluid  synovia; the transparent, viscid fluid secreted by the synovial membrane and found in joint cavities, bursae, and tendon sheaths.

---

interstitial fluid

n.

The fluid in spaces between the tissue cells.

---

Interstitial fluid

The fluid between cells in tissues. Referred to as the liquid subtance of the body.

Mentioned in: Lymphedema

---

interstitial fluid,

an extracellular fluid that fills the spaces between most of the cells of the body and provides a substantial portion of the liquid environment of the body. Formed by filtration through the blood capillaries, it is drained away as lymph. It closely resembles blood plasma in composition but contains less protein. Compare intracellular fluid, lymph, plasma.

---

fluid

1. a liquid or gas; any liquid of the body.

2. composed of molecules which freely change their relative positions without separation of the mass.

---

allantoic fluid

the fluid contained within the allantois.

amniotic fluid

the fluid within the amnion that bathes the developing fetus and protects it from mechanical injury.

ascitic fluid

see ascites.

fluid balance

a state in which the volume of body water and its solutes (electrolytes and nonelectrolytes) are within normal limits and there is normal distribution of fluids within the intracellular and extracellular compartments. The total volume of body fluids should be about 60% of the body weight, and it should be distributed so that one-third is extracellular fluid and two-thirds intracellular fluid. Although this distribution remains constant in a healthy animal, there is continuous movement of fluid into and out of the various compartments. See also dehydration, water intoxication.

body f's

the fluids within the body, composed of water, electrolytes and nonelectrolytes. The volume and distribution of body fluids vary with age, sex and amount of adipose tissue. Throughout life there is a slow decline in the volume of body fluids; obesity decreases the relative amount of water in the body.

Although the body fluids are continuously in motion, moving in and out of the cells, tissue spaces and vascular system, physiologists consider them to be 'compartmentalized'. Fluid within the cell membranes is called intracellular fluid and comprises about two-thirds of the total body fluids. The remaining one-third is outside the cell and is called extracellular fluid. The extracellular fluid can be further divided into tissue fluid (interstitial fluid), which is found in the spaces between the blood vessels and surrounding cells, and intravascular fluid, which is the fluid component of blood.

The maintenance of a proper balance between the intracellular and extracellular fluid volumes is essential to health. In patients with heart failure and renal failure the balance becomes upset, producing either localized or generalized edema. Excessive fluid loss produces fluid volume deficit causing cellular dehydration and impaired cellular function.

Bouin's fluid

a histological fixative.

cerebrospinal fluid

the fluid contained within the ventricles of the brain, the subarachnoid space, and the central canal of the spinal cord. See also cerebrospinal fluid.

fluid dram

see fluid dram.

fluid extract

a liquid preparation of a vegetable drug, containing alcohol as a solvent or preservative, or both, of such strength that each milliliter contains the therapeutic constituents of 1 gram of the standard drug it represents.

fetal fluid

allantoic plus amniotic fluids.

interstitial fluid

the extracellular fluid bathing the cells in most tissues, excluding the fluid within the lymph and blood vessels.

isotonic fluid

having the same tonicity or osmotic pressure as blood.

lacrimal fluid

aqueous fluid secreted by the lacrimal glands; called also tears.

fluid line

in radiographs, the interface between fluid and gas, as in the gastrointestinal tract, will show as a straight line.

fluid loss

by vomiting, diarrhea, polyuria, water deprivation. See dehydration.

fluid mosaic model

the modern concept of the structure of a biological membrane developed by S.J. Singer and G.L. Nicolson. In it the membrane consists of protein molecules partly embedded in a discontinuous bilayer of phospholipids that form the matrix of a mosaic of functional cell units.

fluid ounce

see fluid ounce.

pericardial, pleural, peritoneal fluid

normally present in amounts sufficient only to lubricate the movement of viscera within the respective cavities. Composition similar to blood serum.

fluid replacement

see fluid therapy (below).

fluid restriction

the limitation of oral fluid intake to a prescribed amount for each 24-hour period.

fluid retention

see edema.

spinal fluid

the fluid within the spinal canal.

fluid splashing sounds

audible when gas and fluid are free in a cavity, e.g. abomasum in cases of abomasal displacement; can be elicited by shaking a small animal or part of a large animal (i.e. succussion) or by simultaneous percussion and auscultation.

synovial fluid

synovia.

fluid therapy

aims to replace fluids lost by disease process or by restriction of intake, or to maintain a high rate of fluid excretion to ensure removal of toxins, or to administer therapeutic or anesthetic agents slowly over a long period. The amounts and route of administration vary with the need of the patient. Normal solutions include 5% dextrose and Ringer's solution; alkalinizing fluids include lactated Ringer's and 1.3% sodium bicarbonate; acidifying solutions include isotonic saline and 1.9% ammonium chloride.

fluid thrill

see thrill.

fluid volume deficit

an imbalance in fluid volume in which there is loss of fluid from the body not compensated for by an adequate intake of water. The major causes are: (1) insufficient fluid intake, and (2) excessive fluid loss from vomiting, diarrhea, suctioning of gastric contents, or drainage through operative wounds, burns or fistulae. Decreased volume in the intravascular compartment is called hypovolemia. Because water moves freely between the compartments, extracellular fluid deficit causes intracellular fluid deficit (cellular dehydration), which leaves the cells without adequate water to carry on normal function.

fluid volume excess

an overabundance of water in the interstitial fluid spaces or body cavities (edema) or an excess of fluid within the blood vessels (hypervolemia) and water intoxication.

Factors that contribute to the accumulation of edematous fluid are: (1) dilatation of the arteries, as occurs in the inflammatory process; (2) reduced effective osmotic pressure, as in hypoproteinemia, lymphatic obstruction and increased capillary permeability; (3) increased venous pressure, as in congestive heart failure, thrombophlebitis and cirrhosis of the liver; and (4) retention of sodium due to increased reabsorption of sodium by the renal tubules.

fluid wave

see thrill.

---

interstitial

pertaining to or situated between parts or in the interspaces of a tissue.

---

atypical interstitial pneumonia

see atypical interstitial pneumonia.

interstitial cell adenoma

see interstitial cell tumor (below).

interstitial cell-stimulating hormone

luteinizing hormone.

interstitial cell

the cells of the connective tissue of the ovary or the testis (Leydig's cells), which furnish the internal secretion of those structures.

interstitial cell tumor

a common testicular tumor in old dogs. Most are benign and not associated with any major clinical disturbances but there may be concurrent perianal gland neoplasms, infertility and rarely feminization or viciousness. Called also Leydig cell tumor or interstitial cell adenoma.

interstitial edema

edema of the interstitial interlobular tissue in the lung.

interstitial emphysema

pulmonary emphysema with air accumulated in the interlobular connective tissue; characteristic of emphysema in cattle.

interstitial fluid

the extracellular fluid bathing cells in most tissues, excluding the fluid within the lymph and blood vessels.

interstitial gland

of the ovary, consisting of polyhedral epithelioid cells in the stroma of the ovary and have characteristics of cells which produce steroids.

interstitial nephritis

see nephritis.

interstitial fluid pressure

pressure exerted by the free interstitial fluid; if the pressure is negative this tends to suck fluid out of the vascular system and into the tissue space; if the pressure is greater than the intravascular pressure fluid tends to move out of the tissue space.

interstitial pneumonia

see pneumonia.

interstitial space

tissue space.

interstitial tissue

connective tissue between the cellular elements of a structure.