promoter (redirected from internal promoter)

promoter /pro·mo·ter/ (pro-mo´ter)

1. a segment of DNA usually occurring upstream from a gene coding region and acting as a controlling element in the expression of that gene.

2. a substance in a catalyst that increases its rate of activity.

3. a type of epigenetic carcinogen that promotes neoplastic growth only after initiation by another substance.

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pro·mot·er (pr-mtr)

n.

1. A substance that increases the activity of a catalyst.

2. A DNA molecule to which RNA polymerase binds, initiating the transcription of mRNA.

3. A chemical that may promote carcinogenicity or mutagenicity.

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promoter

a specific DNA sequence to which RNA polymerase binds and signals where RNA synthesis (transcription) should begin.

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internal promoter

a class of enhancers which are gene-specific sequences that increase transcription.

promoter region

the non-coding nucleotide sequence at the transcription start region that is characterized by the presence of a number of conserved or consequence sequences.