intermediate-density lipoprotein


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intermediate-density lipoprotein (IDL)

a lipid-protein complex with a density between those of very-low-density lipoprotein and low-density lipoprotein. The product has a relatively short half-life and is normally in the blood in very low concentrations. In a type III hyperlipoproteinemic state the IDL concentration in the blood is elevated.

intermediate-density lipoprotein

Abbreviation: IDL
Plasma lipids bound to albumin, consisting of lipoproteins with less protein than high-density, but more than low-density lipoproteins.
See also: lipoprotein
References in periodicals archive ?
A principle postprandial lipoprotein is very-low-density lipoprotein (VLDL), which is processed into intermediate-density lipoprotein (IDL), a potent trigger of atherosclerotic plaque growth.
In addition, the Montreal Heart Study showed an independent contribution of increased VLDL remnants (VLDLRs) plus intermediate-density lipoproteins (IDLs) to the progression of CAD and related clinical events (6).
Partially catabolized TG-rich lipoproteins such as intermediate-density lipoproteins and remnant-like particles (RLP) are considered to be highly atherogenic (5).
4 mL) were acquired in duplicate by an automated 360 MHz lipoprotein analyzer, and the lipid methyl signal envelope was decomposed computationally to give the amplitudes of the contributing signals of 16 subclasses [1 for chylomicrons; 6 for VLDL; 1 for intermediate-density lipoprotein (IDL); 3 for LDL; and 5 for HDL].
Because each VLDL, intermediate-density lipoprotein, and LDL particle contains only a single apo B molecule, the serum apo B concentration is a close reflection of the number of such particles present.
Lipoprotein lipase (LPL) is a central enzyme responsible for the hydrolysis of triglycerides in very low-density lipoproteins (VLDLs) and chylomicrons producing intermediate-density lipoproteins (IDLs) and chylomicron remnants, respectively (Li et al.
The plasma lipoproteins are divided into five major classes based on their relative density: chylomicrons, Very Low-Density Lipoproteins (VLDLs), Intermediate-Density Lipoproteins (IDLs), Low-Density Lipoproteins (LDLs), and High-Density Lipoproteins (HDLs).
The association of increased levels of intermediate-density lipoproteins with smoking and with coronary artery disease.
beta-lipoproteins, a collective group of chylomicrons, very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), and LDL, each containing a single molecule of apolipoprotein B (apoB).
Familial type III hyperlipoproteinemia is a genetic disorder in which the plasma concentrations of both cholesterol and triglycerides are elevated as a result of the accumulation of chylomicron remnants and intermediate-density lipoproteins (IDL).
In contrast to the earlier two studies, the men whose lipid profiles changed in this test also exhibited an increase in blood concentrations of intermediate-density lipoproteins (IDLs).
These lipoproteins include chylomicrons, VLDL, and intermediate-density lipoproteins (IDL).

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