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intermediate-density lipoprotein

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
lipoprotein /lipo·pro·tein/ (-prō´tēn) a complex of lipids and apolipoproteins, the form in which lipids are transported in the blood.
α-lipoprotein , alpha lipoprotein one with electrophoretic mobility equivalent to that of the α1-globulins, e.g., high-density lipoprotein.
β-lipoprotein , beta lipoprotein one with electrophoretic mobility equivalent to that of the β-globulins, e.g., low-density lipoprotein.
floating beta lipoproteins  β.
high-density lipoprotein  (HDL) a class of plasma lipoproteins that promote transport of cholesterol from extrahepatic tissue to the liver for excretion in the bile; serum levels have been negatively correlated with premature coronary heart disease.
intermediate-density lipoprotein  (IDL) a class of lipoproteins formed in the degradation of very-low-density lipoproteins; some are cleared rapidly into the liver and some are degraded to low-density lipoproteins.
low-density lipoprotein  (LDL) a class of plasma lipoproteins that transport cholesterol to extrahepatic tissues; high serum levels have been correlated with premature coronary heart disease.
Lp(a) lipoprotein  a lipoprotein particle containing apolipoprotein B-100 as well as an antigenically unique apolipoprotein; its occurrence at high levels in plasma has been correlated with increased risk of heart disease.
pre-β-lipoprotein , pre-beta lipoprotein very-low-density lipoprotein
sinking pre-β-lipoprotein  Lp(a) l.
very-high-density lipoprotein  (VHDL) a class of lipoproteins composed predominantly of proteins and also containing a high concentration of free fatty acids.
very-low-density lipoprotein  (VLDL) a class of lipoproteins that transport triglycerides from the intestine and liver to adipose and muscle tissues; they contain primarily triglycerides with some cholesteryl esters.

intermediate-density lipoprotein (IDL),
a lipid-protein complex with a density between those of very low-density lipoprotein and low-density lipoprotein. The product has a relatively short half-life and is normally in the blood in very low concentrations. In a type III hyperlipoproteinemic state the IDL concentration in the blood is elevated.


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The remnants of CM and VLDL, after LPL has hydrolysed triglycerides, are smaller and denser and eventually enter the intermediate-density lipoprotein (IDL) category.
Because particles of LDL, intermediate-density lipoprotein (IDL) and VLDL each contain one apolipoprotein B (ApoB) protein, ApoB concentration may give a better indication of large lipoprotein particle concentration than measurements of cholesterol concentrations alone.
Furthermore, these calculated LDL-C values include also intermediate-density lipoprotein cholesterol (IDL-C) levels and lipoprotein (a) to varying degrees.
 
 
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