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intermediate density lipoprotein

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intermediate density lipoprotein
Physiology A plasma lipoprotein with a density of 1.006-1.019 g/dl, formed by lipoprotein lipase hydrolysis of VLDL partially depleted of TGs Composition 15% protein, predominantly apoB and apoE, 25% phospholipid, 30% cholesterol, 30% TGs Role Transports cholesterol from intestine to liver; once in the liver, is delipidated by hepatic lipoprotein lipase to form a low-density protein


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If we neglect serum intermediate density lipoprotein (IDL) and lipoprotein(a) [Lp(a)] concentrations, we can write non-HDL cholesterol=LDL cholesterol + VLDL cholesterol [1].
These cholesteryl esters are transported throughout the body in lipoprotein particles that are classified according to the ratio of protein to fat, or more simply, the density of the particle, in the following increasing order: chylomicrons, very low-density lipoprotein, intermediate density lipoprotein, low-density lipoprotein (LDL), and high-density lipoprotein (HDL).
Chylomicrons are the largest particles, the very low density lipoprotein (VLDL) is the next largest, the intermediate density lipoprotein (IDL) is the next largest, the low density lipoprotein (IDL) is the next largest, and then high density lipoproteins (HDL) are the smallest.
 
 
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