IL25

(redirected from interleukin-17E)

IL25

A gene on chromosome 14q11.2 that encodes interluekin-25, a proinflammatory cytokine that induces activation of NF-kappa-B and stimulates proinflammatory IL-8 production. IL25 favours Th2-type immune responses.
References in periodicals archive ?
Twelve proteins including human interleukin-17E, eukaryotic translation initiation factor 5A (elF5A), peroxiredoxin 2, ubiquilin 2, Cu/Zn-superoxide dismutase, 14-3-3 beta/alpha, TPM4-ALK fusion oncoprotein type 2, PP2A subunit A PR65-alpha isoform, nucleobindin-1, heterogeneous nuclear ribonucleoprotein K, reticulocalbin 1 and chain A of DJ-1 protein were identified.
The biotechnology firm said its experimental candidate Interleukin-17E (IL-17E) showed antitumor effects in melanoma, breast, colon, pancreatic and non-small-cell lung cancers, both alone and in combination with a number of approved cancer drugs.