interferon alpha


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in·ter·fer·on al·pha

the major interferon made by virus-induced leukocytes; several different subtypes exist that are elaborated by leukocytes in response to viral infection or to stimulation with double-stranded RNA. There are 14 genes on the short arm of chromosome 9 that code for these substances in humans. IFN-α-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents.

interferon alpha

Interferon alpha

Potent immune-defense protein; used as an anti-cancer drug.

in·ter·fer·on al·pha

(intĕr-fēron alfă)
The major interferon made by virus-induced leukocytes; several subtypes exist that are elaborated by leukocytes in response to viral stimulation.
References in periodicals archive ?
Conclusion: Interferon alpha receptors 1-messenger ribonucleic acid may be useful for predicting response to interferon plus ribavirin therapy in hepatitis C virus/ hepatitis B virus co-infected patients who were females with lower hepatitis C virus-ribonucleic acid and hepatitis B virus-deoxyribonucleic acid levels.
Despite the development of thyroid disorders (overt and sub-clinical), patients completed their antiviral therapy with Interferon alpha and ribavirin.
Pericarditis secondary to interferon alpha in chronic hepatitis C].
The interferon alpha shots stimulated a robust immune cell response in the animals, and the antibodies, delivered intravenously, blocked virus entry into cells.
This ongoing open label clinical trial plans to enroll a total of 50 hepatitis C non-responder patients, none of which have responded to prior therapy of at least six months of interferon alpha in combination with ribavirin.
Now, no one else will be able to produce a lozenge or tablet with interferon alpha without risk of infringing this patent , which will provide protection for the low dose oral delivery of interferon for 17 years from the date of issue.
HCV infected patients without any laboratory evidence of autoimmunity were included in the study and this population was divided in to a test group (36) who were treated with interferon alpha and a control group (32) who did not receive anti viral treatment during this period.
Development of thyroid disease during therapy of chronic viral hepatitis with interferon alpha.
In each of the clinical trials, patients are assigned to a 12-month course of either ZADAXIN and pegylated interferon alpha or placebo and pegylated interferon alpha.
Ribavirin and interferon alpha 2-b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interaction.
It also presents a valuable option for CML patients with chronic disease that hasn't responded to interferon alpha, the best drug now available, he says.