intention to treat

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intention to treat

In clinical trials, the principle that holds that the effect of a treatment regimen can be best assessed by evaluating the basis of the intention to treat a subject (i.e., the planned treatment regimen), rather than the actual treatment given. Thus, subjects allocated to a treatment group should be followed, assessed and analysed as members of the treatment group irrespective of their compliance with the planned course of treatment. The principle of intention to treat is meant to prevent bias caused by loss of trial participants, which may reflect non-adherence to the protocol and disrupt baseline equivalence established by random assignment.
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We added a time-dependent interaction effect with the radiotherapy indicator to assess the consistency of our main findings (overall, low and high risk intent to treat results) over time.
Thoratec said forty-six percent of the HeartMate II patients successfully achieved the primary composite endpoint of survival at two years while remaining free from disabling stroke or the need for reoperation to replace or repair the pump versus 11% of the SVE patient cohort, on an intent to treat basis.
Moreover, the phrase "symptoms for which you received medical care" connotes an intent to treat or uncover the particular ailment that causes that symptom--even absent a timely diagnosis--rather than some nebulous or unspecified medical problem.
In another type of analysis, known as intent to treat, researchers include the consequences of a drug's side effects and dosing schedule and count all the patients in a study, whether they take the medication or not.
The Seventh Circuit disagreed since the taxpayers had not clearly indicated on their 1994 return their intent to treat the rentals as a single activity.
An economic benefit is not consideration for the performance of services, unless the organization providing the benefit clearly indicates its intent to treat the benefit as compensation when it is paid.
The legislative history of section 902 evinces congressional intent to treat foreign subsidiaries and branches similarly.
The clinical cure rates in the modified intent to treat population and the per protocol population observed in this trial with cethromycin were in line with cethromycin phase 2 results and with clinical cure rates observed with currently marketed antibiotics.
Although the court in Compaq "shammed" the ADR transactions (because Compaq eliminated virtually all market risk), the IES Industries court actually noted that the carefully orchestrated elimination of market risk was evidence of IES Industries' intent to treat the ADR transactions as moneymaking.
By intent to treat analysis at 48 weeks, 47% of patients in group C (quadruple therapy) had viral loads less than 50 copies/mL compared to 42%, 38% and 26% for groups A, B and D, respectively.
all patients with a baseline ACR and a 6-month ACR) were included in the Intent to Treat analysis, for a total of 136 patients in the Intent to Treat population.
4958-4(c), an economic benefit is not consideration for services unless the organization providing the benefit clearly indicates its intent to treat the benefit as compensation when paid.